Navio Robotic Versus Conventional Total Knee Arthroplasty

Description

Total knee replacement surgery is a conventional approach to alleviating the pain and lack of function resulting from arthritis of the knee. While conventional knee replacement surgery is highly successful, incidences of improperly installed replacement parts are not uncommon. To improve outcomes, robotic-assisted total knee replacement surgery has recently become available, and has been shown to be extremely effective for partial knee replacement surgery. However, further research is needed to determine if this same technology can be equally effective for total knee replacement surgery. The present study will evaluate outcomes of robotic-assisted versus conventional total knee replacement surgery in patients between 40 and 85 years old with end stage arthritis of the knee. Other than surgical technique, patients will receive the same operative care and knee replacement implants. In addition to standard x-rays, subjects will be asked to complete several short-term clinical and functional tests and questionnaires to determine outcomes of their surgery.

Conditions

Osteoarthritis, Knee

Study Overview

Study Details

Study overview

Total knee replacement surgery is a conventional approach to alleviating the pain and lack of function resulting from arthritis of the knee. While conventional knee replacement surgery is highly successful, incidences of improperly installed replacement parts are not uncommon. To improve outcomes, robotic-assisted total knee replacement surgery has recently become available, and has been shown to be extremely effective for partial knee replacement surgery. However, further research is needed to determine if this same technology can be equally effective for total knee replacement surgery. The present study will evaluate outcomes of robotic-assisted versus conventional total knee replacement surgery in patients between 40 and 85 years old with end stage arthritis of the knee. Other than surgical technique, patients will receive the same operative care and knee replacement implants. In addition to standard x-rays, subjects will be asked to complete several short-term clinical and functional tests and questionnaires to determine outcomes of their surgery.

Conventional vs. Robotic-Assisted Total Knee Arthroplasty: A Prospective, Randomized Trial of Clinical, Functional, and Radiographic Outcomes

Navio Robotic Versus Conventional Total Knee Arthroplasty

Condition
Osteoarthritis, Knee
Intervention / Treatment

-

Contacts and Locations

New York

Columbia University Medical Center, New York, New York, United States, 10032

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * age between 40 and 85
  • * body mass index (BMI) less than 40.0 kg/m\^2
  • * end-stage knee osteoarthritis (Kellgren and Lawrence grade 4)
  • * failure of a minimum 12 weeks of nonoperative management
  • * English fluency
  • * history of inflammatory arthropathy in the same knee
  • * history of prior open knee surgery in the same knee
  • * history of prior osteotomy or periarticular fracture
  • * deformity \> 15 degrees from a neutral mechanical axis
  • * gross ligamentous incompetence of the medial or lateral collateral ligaments
  • * musculoskeletal involvement beyond unilateral knee osteoarthritis significantly limiting their function
  • * unwillingness or inability to participate in the proposed study protocol and follow-up

Ages Eligible for Study

40 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Columbia University,

Herbert John Cooper, MD, PRINCIPAL_INVESTIGATOR, Columbia University

Study Record Dates

2025-12