ACTIVE_NOT_RECRUITING

Overnight Fasting After Completion of Therapy: The OnFACT Study

Conditions

Childhood Cancer Survivors Fasting 18-199

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to test whether regularly not eating for at least 14 hours overnight ("intermittent fasting") is feasible and can improve blood sugar.

Official Title

Overnight Fasting After Completion of Therapy: The OnFACT Study

Quick Facts

Study Start:2018-04-27

Study Completion:2026-04

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:ACTIVE_NOT_RECRUITING

Study ID

NCT03523377

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Body mass index is ≥ 18.5 kg/m\^2 * History of treatment for cancer or related illness diagnosed at ≤ 25 years old * Off cytotoxic therapy for primary cancer ≥ 2 years * Not receiving cytotoxic therapy (chemotherapy, external beam radiation therapy) at the time of study enrollment * History of radiation to the chest, abdomen or total body * Current age ≥18 years * English-speaking * Personal phone with SMS text messaging capability * Willingness to wear an mHealth device, such as a FitBit, for two 7-day periods * Able to perform all study requirements	* Use of any antidiabetic, weight loss, or appetite control medication * Use of any other medication that could impact dietary intake, such as prednisone * Currently fasts 12 hours or more by self-report * Unable to fast due to medical reason such as pregnancy

Inclusion Criteria

Exclusion Criteria

* Body mass index is ≥ 18.5 kg/m\^2
* History of treatment for cancer or related illness diagnosed at ≤ 25 years old
* Off cytotoxic therapy for primary cancer ≥ 2 years
* Not receiving cytotoxic therapy (chemotherapy, external beam radiation therapy) at the time of study enrollment
* History of radiation to the chest, abdomen or total body
* Current age ≥18 years
* English-speaking
* Personal phone with SMS text messaging capability
* Willingness to wear an mHealth device, such as a FitBit, for two 7-day periods
* Able to perform all study requirements

* Use of any antidiabetic, weight loss, or appetite control medication
* Use of any other medication that could impact dietary intake, such as prednisone
* Currently fasts 12 hours or more by self-report
* Unable to fast due to medical reason such as pregnancy

Contacts and Locations

Principal Investigator

Danielle Friedman, MD, MS

PRINCIPAL_INVESTIGATOR

Memorial Sloan Kettering Cancer Center

Study Locations (Sites)

Memorial Sloan Kettering Cancer Center

New York, New York, 10065

United States

Collaborators and Investigators

Sponsor: Memorial Sloan Kettering Cancer Center

Danielle Friedman, MD, MS, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-04-27

Study Completion Date2026-04

Study Record Updates

Study Start Date2018-04-27

Study Completion Date2026-04

Terms related to this study

Keywords Provided by Researchers

Fasting
18-199

Additional Relevant MeSH Terms

Childhood Cancer Survivors