RECRUITING

Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients

Conditions

Pediatric Retinoblastoma Retinoblastoma 18-126 Memorial Sloan Kettering Cancer Center

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.

Official Title

Incidence of Neurocognitive Deficits in Patients After Treatment for Retinoblastoma With Multiple Anesthesia Exposures

Quick Facts

Study Start:2018-05-07

Study Completion:2025-05-07

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT03546387

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:6 Years to 17 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:CHILD

Inclusion Criteria	Exclusion Criteria
* Age ≥ 6 and \< 17 years old	* Diagnosis of any secondary disease associated with developmental delay * History of second cancer diagnosis * Legal Blindness * Past surgery of any type, with the exception of enucleation for retinoblastoma * Past exposure to anesthesia for purposes other than retinoblastoma examination * More than one anesthesia encounter before diagnosis at MSK * Past External Beam Radiation for treatment of retinoblastoma * Past systemic chemotherapy * Non-native speaker of English; however, children whose parents speak only Spanish will be included, because the tests for parents are available in Spanish

Inclusion Criteria

Exclusion Criteria

* Age ≥ 6 and \< 17 years old

* Diagnosis of any secondary disease associated with developmental delay
* History of second cancer diagnosis
* Legal Blindness
* Past surgery of any type, with the exception of enucleation for retinoblastoma
* Past exposure to anesthesia for purposes other than retinoblastoma examination
* More than one anesthesia encounter before diagnosis at MSK
* Past External Beam Radiation for treatment of retinoblastoma
* Past systemic chemotherapy
* Non-native speaker of English; however, children whose parents speak only Spanish will be included, because the tests for parents are available in Spanish

Contacts and Locations

Study Contact

Vittoria Arslan Carlon, MD

CONTACT

212-639-2680

arslancv@mskcc.org

David Abramson, MD

CONTACT

212-639-7232

abramsod@mskcc.org

Principal Investigator

Vittoria Arslan Carlon, MD

PRINCIPAL_INVESTIGATOR

Memorial Sloan Kettering Cancer Center

Study Locations (Sites)

Memorial Sloan Kettering Cancer Center

New York, New York, 10065

United States

Collaborators and Investigators

Sponsor: Memorial Sloan Kettering Cancer Center

Vittoria Arslan Carlon, MD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-05-07

Study Completion Date2025-05-07

Study Record Updates

Study Start Date2018-05-07

Study Completion Date2025-05-07

Terms related to this study

Keywords Provided by Researchers

18-126
Memorial Sloan Kettering Cancer Center

Additional Relevant MeSH Terms

Pediatric Retinoblastoma
Retinoblastoma