Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients

Description

The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.

Conditions

Pediatric Retinoblastoma, Retinoblastoma

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Study Overview

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Study Details

Study overview

The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.

Incidence of Neurocognitive Deficits in Patients After Treatment for Retinoblastoma With Multiple Anesthesia Exposures

Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients

Condition
Pediatric Retinoblastoma
Intervention / Treatment

-

Contacts and Locations

New York

Memorial Sloan Kettering Cancer Center, New York, New York, United States, 10065

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age ≥ 6 and \< 17 years old
  • * Diagnosis of any secondary disease associated with developmental delay
  • * History of second cancer diagnosis
  • * Legal Blindness
  • * Past surgery of any type, with the exception of enucleation for retinoblastoma
  • * Past exposure to anesthesia for purposes other than retinoblastoma examination
  • * More than one anesthesia encounter before diagnosis at MSK
  • * Past External Beam Radiation for treatment of retinoblastoma
  • * Past systemic chemotherapy
  • * Non-native speaker of English; however, children whose parents speak only Spanish will be included, because the tests for parents are available in Spanish

Ages Eligible for Study

6 Years to 17 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Memorial Sloan Kettering Cancer Center,

Vittoria Arslan Carlon, MD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

2025-05-07