The Effect of IBD Flares on Serum PSA

Description

This study will measure Prostate Specific Antigen (PSA) values in men with Inflammatory Bowel Disease (IBD) before, during, and following a flare. In addition, the effect of any PSA increase will be analyzed and correlated to the location of disease (rectal vs. other). Study findings may help men with IBD by identifying pitfalls in prostate cancer screening for this population and help to stratify and understand the effect IBD has on the prostatic milieu. By optimizing how men with IBD are screened for prostate cancer, future unnecessary healthcare encounters and expenditures may be reduced for this patient group.

Conditions

Inflammatory Bowel Diseases, Prostate Cancer

Study Overview

Study Details

Study overview

This study will measure Prostate Specific Antigen (PSA) values in men with Inflammatory Bowel Disease (IBD) before, during, and following a flare. In addition, the effect of any PSA increase will be analyzed and correlated to the location of disease (rectal vs. other). Study findings may help men with IBD by identifying pitfalls in prostate cancer screening for this population and help to stratify and understand the effect IBD has on the prostatic milieu. By optimizing how men with IBD are screened for prostate cancer, future unnecessary healthcare encounters and expenditures may be reduced for this patient group.

The Effect of Inflammatory Bowel Disease Flares on Serum Prostate Specific Antigen

The Effect of IBD Flares on Serum PSA

Condition
Inflammatory Bowel Diseases
Intervention / Treatment

-

Contacts and Locations

Chicago

Northwestern Medicine, Chicago, Illinois, United States, 60611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Men, ages 40-69 years old
  • * Confirmed diagnosis of IBD presenting to the Northwestern Memorial Hospital Gastroenterology Clinic
  • * History of prostate cancer or prior prostate procedures (biopsies or transurethral resection)

Ages Eligible for Study

40 Years to 69 Years

Sexes Eligible for Study

MALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Northwestern University,

Study Record Dates

2025-10-01