Blood Markers of Early Pancreas Cancer

Description

Identifying biomarkers of early pancreatic ductal adenocarcinoma (PDAC) could facilitate screening for individuals at higher than average risk and expedite the diagnosis in individuals with symptoms and substantially improve an individual's chance of surviving the disease. The investigators propose a longitudinal study of subjects at higher than average risk of PDAC in order to generate clinical data and bank serial blood specimens.

Conditions

Diabetes Mellitus, Type 2, PreDiabetes, Pancreas Cyst, Chronic Pancreatitis, Genetic Predisposition to Disease, Inherited Disease

Study Overview

Study Details

Study overview

Identifying biomarkers of early pancreatic ductal adenocarcinoma (PDAC) could facilitate screening for individuals at higher than average risk and expedite the diagnosis in individuals with symptoms and substantially improve an individual's chance of surviving the disease. The investigators propose a longitudinal study of subjects at higher than average risk of PDAC in order to generate clinical data and bank serial blood specimens.

A Longitudinal Cohort Study to Identify Clinical and Blood Markers of Early Pancreas Cancer

Blood Markers of Early Pancreas Cancer

Condition
Diabetes Mellitus, Type 2
Intervention / Treatment

-

Contacts and Locations

Omaha

Unversity of Nebraska Medical Center, Omaha, Nebraska, United States, 68198

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age ≥19
  • * Able to provide written, informed consent
  • * Able to attend an in-person study visit in Omaha, NE twice a year to collect blood samples
  • * Must also meet criteria for one specific cohort. Participants who meet criteria for more than one cohort are eligible.
  • * Personal history of pancreatic ductal adenocarcinoma (PDAC)
  • * Currently receiving treatment for a cancer diagnosis (excluding long-term hormonal therapy)
  • * Pre-diabetes on metformin for ≥ 3 years

Ages Eligible for Study

19 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Nebraska,

Kelsey A Klute, MD, PRINCIPAL_INVESTIGATOR, University of Nebraska

Study Record Dates

2028-07