The APOLLO study is being done in an attempt to improve outcomes after kidney transplantation and to improve the safety of living kidney donation based upon variation in the apolipoprotein L1 gene (APOL1). Genes control what is inherited from a family, such as eye color or blood type. Variation in APOL1 can cause kidney disease. African Americans, Afro-Caribbeans, Hispanic Blacks, and Africans are more likely to have the APOL1 gene variants that cause kidney disease. APOLLO will test DNA from kidney donors and recipients of kidney transplants for APOL1 to determine effects on kidney transplant-related outcomes.
Kidney Diseases, Kidney Failure, Kidney Disease, Chronic
The APOLLO study is being done in an attempt to improve outcomes after kidney transplantation and to improve the safety of living kidney donation based upon variation in the apolipoprotein L1 gene (APOL1). Genes control what is inherited from a family, such as eye color or blood type. Variation in APOL1 can cause kidney disease. African Americans, Afro-Caribbeans, Hispanic Blacks, and Africans are more likely to have the APOL1 gene variants that cause kidney disease. APOLLO will test DNA from kidney donors and recipients of kidney transplants for APOL1 to determine effects on kidney transplant-related outcomes.
APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)
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University of Alabama at Birmingham, Birmingham, Alabama, United States, 35233
University of California San Francisco, San Francisco, California, United States, 94143
University of Miami / Miami Transplant Institute, Miami, Florida, United States, 33133
Emory University School of Medicine, Atlanta, Georgia, United States, 30322
University of Maryland School of Medicine, Baltimore, Maryland, United States, 21201
Johns Hopkins University, Baltimore, Maryland, United States, 21205
Joslin Diabetes Center / Harvard University, Boston, Massachusetts, United States, 02215
University of Michigan Medicine, Ann Arbor, Michigan, United States, 48109
Saint Louis University Center for Transplantation, Saint Louis, Missouri, United States, 63104
Ichan School of Medicine at Mount Sinai, New York, New York, United States, 10029
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
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Wake Forest University Health Sciences,
Barry I. Freedman, MD, PRINCIPAL_INVESTIGATOR, Wake Forest University Health Sciences
David M. Reboussin, PhD, PRINCIPAL_INVESTIGATOR, Wake Forest University Health Sciences
Paul L. Kimmel, MD, STUDY_DIRECTOR, Natl Institute of Diabetes, Digestive & Kidney Diseases
Marva Moxey-Mims, MD, STUDY_CHAIR, Children's Natl Health System; George Washington Univ Sch of Med and Health Serv
2025-12-31