Vitamin D Homeostasis in Sarcoidosis

Description

This study evaluates the relationship between vitamin-D status and severity of sarcoidosis, and the effects of vitamin-D repletion in vitamin-D insufficient patients with sarcoidosis. Half the patients with sarcoidosis who are vitamin-D insufficient will receive standard vitamin-D supplementation via standard regimen while the other half will receive a placebo. Sarcoidosis patients who are vitamin-D sufficient will also act as controls.

Conditions

Sarcoidosis, Vitamin D Insufficiency

Study Overview

Study Details

Study overview

This study evaluates the relationship between vitamin-D status and severity of sarcoidosis, and the effects of vitamin-D repletion in vitamin-D insufficient patients with sarcoidosis. Half the patients with sarcoidosis who are vitamin-D insufficient will receive standard vitamin-D supplementation via standard regimen while the other half will receive a placebo. Sarcoidosis patients who are vitamin-D sufficient will also act as controls.

Vitamin D Homeostasis in Sarcoidosis

Vitamin D Homeostasis in Sarcoidosis

Condition
Sarcoidosis
Intervention / Treatment

-

Contacts and Locations

Dallas

University of Texas Southwestern Medical Center, and Parkland Health and Hospital System, Dallas, Texas, United States, 75390-9034

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Stable medical condition defined as no hospitalization or emergency room visit in the previous 3 months
  • * No evidence of active pulmonary or systemic infection
  • * No other active inflammatory disease,
  • * No active malignancy.
  • * Normal serum ionized calcium level
  • * Hospitalization or emergency room visit in the previous 3 months
  • * Evidence of active pulmonary or systemic infection
  • * Evidence of active other inflammatory disease
  • * Evidence of active malignancy
  • * Elevated serum ionized calcium level

Ages Eligible for Study

21 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Texas Southwestern Medical Center,

Connie Hsia, MD, PRINCIPAL_INVESTIGATOR, University of Texas Southwestern Medical Center

Study Record Dates

2026-12-30