Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy

Description

The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg/kg given 2) to record the time to first analgesic postoperatively and 3) to compare Wong Baker and the 0-10 numeric pain distress scale scores at 12, 24 and 48 hours postoperatively. We hypothesize one 15mg/kg (up to 600mg) dose of gabapentin will decrease mean narcotic amounts in mg/kg compared to participants who do not receive preoperative gabapentin and will demonstrate a decreased mean time to first analgesic as well as to lower mean pain scores for each age group at 12, 24 and 48 hours.

Conditions

Tonsillitis, Tonsillectomy

Study Overview

Study Details

Study overview

The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg/kg given 2) to record the time to first analgesic postoperatively and 3) to compare Wong Baker and the 0-10 numeric pain distress scale scores at 12, 24 and 48 hours postoperatively. We hypothesize one 15mg/kg (up to 600mg) dose of gabapentin will decrease mean narcotic amounts in mg/kg compared to participants who do not receive preoperative gabapentin and will demonstrate a decreased mean time to first analgesic as well as to lower mean pain scores for each age group at 12, 24 and 48 hours.

Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy/Adenoidectomy: Randomized Control Trial

Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy

Condition
Tonsillitis
Intervention / Treatment

-

Contacts and Locations

Atlanta

Children's Healthcare of Atlanta, Atlanta, Georgia, United States, 30329

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * participants age 3-18 years
  • * ASA class 1 or 2
  • * elective Tonsillectomy/Adenoidectomy
  • * outpatient setting.
  • * BMI \>40kg/m2
  • * history of renal insufficiency, chronic pain
  • * allergy to gabapentin
  • * history of developmental delay

Ages Eligible for Study

3 Years to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Children's Healthcare of Atlanta,

Christina Calamaro, PhD, CPNP-PC, STUDY_CHAIR, Institutional Review Board

Study Record Dates

2019-12-31