RECRUITING

NSAIDs Stent Study

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Conditions

Ureteral Stent PlacementKidney Stone

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a pilot study to (1) evaluate the effect of Ketorolac on inflammatory response and its impact on stent related symptoms in patients undergoing stent placement procedure and (2) assess feasibility of recruitment, randomization, assessment procedures and implementation of the study intervention.

Official Title

A Prospective, Randomized, Pilot Study of Preoperative Anti-Inflammatory Therapy for Ureteral Stent Symptoms

Quick Facts

Study Start:2018-07-31
Study Completion:2026-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03638999

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Over 18 years of age and willing and able to provide informed consent
  2. * Patients with renal urolithiasis planning to undergo ureteral stent placement following ureteroscopic manipulation
  1. * Patients requiring a bilateral stone procedure.
  2. * Patients on a chronic non-steroidal anti-inflammatory drugs (NSAIDs) including Aspirin defined as any NSAIDs use for more than fifteen days within thirty days prior to the procedure. Exception: use of daily Aspirin 81 mg is allowed.
  3. * Patients on any steroid therapy.
  4. * Patients with prescription anti-inflammatory drugs.
  5. * Patients with gastrointestinal ulcers.
  6. * Patients with ureteral obstruction or stricture unrelated to stone disease.
  7. * Patients with active urinary tract infection as evidence of untreated positive urine culture obtained prior to the procedure (as part of pre-operative testing).
  8. * Patients with preexisting indwelling ureteral stent
  9. * Patients who are pregnant or lactating.
  10. * Patients with renal or liver impairment.
  11. * Patients with concurrent disease, infection, or co-morbidity that, in the judgment of the investigator, would render the patient inappropriate for enrollment.

Contacts and Locations

Study Contact

Alana Desai, MD
CONTACT
(314)
desaia@email.wustl.edu
Karla Bergeron, CCRP
CONTACT
(314) 454-7325
bergeronk@email.wustl.edu

Principal Investigator

Alana Desai, MD
PRINCIPAL_INVESTIGATOR
Washington University School of Medicine

Study Locations (Sites)

Washington University
Saint Louis, Missouri, 63110
United States

Collaborators and Investigators

Sponsor: Washington University School of Medicine

  • Alana Desai, MD, PRINCIPAL_INVESTIGATOR, Washington University School of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-07-31
Study Completion Date2026-10

Study Record Updates

Study Start Date2018-07-31
Study Completion Date2026-10

Terms related to this study

Additional Relevant MeSH Terms

  • Ureteral Stent Placement
  • Kidney Stone