RECRUITING

Executive Function in Early Childhood

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Despite the fact that a substantial number of school age children struggle with both reading and math acquisition, the brain mechanisms of the overlapping aspects of reading and math skills, thought in part to be linked via executive functions (EF), have not been unpacked. This project will use a longitudinal design, following children from Kindergarten through 1st grade, to understand how the brain networks associated with reading, math, and EF interact to predict academic outcomes and, in those who struggle academically, intervention response.

Official Title

Early Academic Achievement and Intervention Response: Role of Executive Function

Quick Facts

Study Start:2019-08-13
Study Completion:2025-07-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03713125

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:4 Years to 9 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. 1. Children in Kindergarten (approximate ages 4-9 years)
  2. 2. Native English speakers
  1. 1. Children not in Kindergarten at time of enrollment;
  2. 2. previous diagnosis of Intellectual Disability;
  3. 3. known uncorrectable visual impairment;
  4. 4. documented hearing impairment greater than or equal to a 25 decibel (dB) loss;
  5. 5. medical contraindication to MRI procedures (e.g., metal devices) - excludes from MRI procedures only;
  6. 6. known intelligence quotient (IQ) below 70;
  7. 7. a pervasive developmental disorder; and
  8. 8. any known neurologic pathology, including epilepsy, spina bifida, cerebral palsy, traumatic brain injury, and brain tumors.
  9. 9. Comorbid severe psychiatric disorders will also be excluded, as will those who are taking psychotropic medications, with the exception of stimulant medication for Attention Deficit Hyperactivity Disorder (ADHD). Children who meet criteria for ADHD will be eligible as long as they are not taking psychotropic medications, with the exception of stimulant medication for ADHD.

Contacts and Locations

Study Contact

Julie Delheimer, BS
CONTACT
615-875-5534
educationbrain@vanderbilt.edu
Lanier P Sachs, M.Ed.
CONTACT
615-936-1167

Principal Investigator

Laurie E Cutting, PhD
PRINCIPAL_INVESTIGATOR
Vanderbilt University

Study Locations (Sites)

Vanderbilt University
Nashville, Tennessee, 37240
United States

Collaborators and Investigators

Sponsor: Vanderbilt University

  • Laurie E Cutting, PhD, PRINCIPAL_INVESTIGATOR, Vanderbilt University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-08-13
Study Completion Date2025-07-31

Study Record Updates

Study Start Date2019-08-13
Study Completion Date2025-07-31

Terms related to this study

Additional Relevant MeSH Terms

  • Reading Disability