Effect of Theophylline in Pseudohypoparathyroidism

Description

The study evaluates the effect of theophylline in 100 subjects with Pseudohypoparathyroidism.

Conditions

PHP Ia, PHP IB, Php1C

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Study Overview

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Study Details

Study overview

The study evaluates the effect of theophylline in 100 subjects with Pseudohypoparathyroidism.

Effect of Theophylline in Pseudohypoparathyroidism

Effect of Theophylline in Pseudohypoparathyroidism

Condition
PHP Ia
Intervention / Treatment

-

Contacts and Locations

Boston

Massachusetts General Hospital, Boston, Massachusetts, United States, 02114

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Subjects with known diagnosis of PHP1A and PHP1B
  • * Age \>5 years
  • * • Significant kidney disease, i.e. any CKD stage
  • * Hypercalciuria
  • * Kidney stones
  • * Severe Heart disease
  • * Uncontrolled seizure disorder
  • * Peptic ulcer
  • * Liver dysfunction
  • * Bleeding disorder
  • * Allergy to theophylline preparation
  • * Muscle disorder
  • * Infection
  • * Any neurologic disease
  • * Chronic drugs interacting with theophylline

Ages Eligible for Study

5 Years to 21 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Massachusetts General Hospital,

AMITA SHARMA, MD, PRINCIPAL_INVESTIGATOR, Massachusetts General Hospital

Study Record Dates

2032-04-10