RECRUITING

An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The immediate goal of the proposed research is to test the value of a new low-cost, low-dose standing CT system for efficient early detection of both joint degeneration and elevated contact stress. The standing CT scanner holds promise for detecting arthritic changes earlier than other imaging modalities because of the combination of its 3D nature and ability to image joints in a weight-bearing pose. A secondary goal of the proposed research is to enable predictive models for osteoarthritis risk based on measures of post treatment contact stress, both to inform treatment and so that new interventions can be tested in a manner incorporating risk stratification.

Official Title

An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA

Quick Facts

Study Start:2017-01-01
Study Completion:2024-12-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03809520

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Individuals 18 to 70 years old Sustained an intra-articular fracture of the tibial plafond Indicated for operative treatment Present for treatment within 4 weeks of injury
  1. * Women who are pregnant or planning on becoming pregnant Individuals younger than 18 and older than 70

Contacts and Locations

Study Contact

Catherine Fruehling, BA
CONTACT
3194678256
catherine-fruehling@uiowa.edu

Principal Investigator

J L Marsh, MD
PRINCIPAL_INVESTIGATOR
University of Iowa

Study Locations (Sites)

University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242
United States

Collaborators and Investigators

Sponsor: J L Marsh

  • J L Marsh, MD, PRINCIPAL_INVESTIGATOR, University of Iowa

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-01-01
Study Completion Date2024-12-30

Study Record Updates

Study Start Date2017-01-01
Study Completion Date2024-12-30

Terms related to this study

Additional Relevant MeSH Terms

  • Orthopedic Disorder
  • Trauma
  • Ankle Fractures
  • Post-traumatic Osteoarthritis