Physiology, Imaging and Modeling of Essential Tremor

Description

This project aims to investigate novel ways to deliver brain stimulation to Essential Tremor (ET) patients by introducing software changes to their existing devices. The study team aims to investigate safety and efficacy of these new stimulation parameters in patients with ET.

Conditions

Essential Tremor, Parkinson Disease, Dystonia

Study Overview

Study Details

Study overview

This project aims to investigate novel ways to deliver brain stimulation to Essential Tremor (ET) patients by introducing software changes to their existing devices. The study team aims to investigate safety and efficacy of these new stimulation parameters in patients with ET.

Physiology, Imaging and Modeling of Deep Brain Stimulation for Essential Tremor

Physiology, Imaging and Modeling of Essential Tremor

Condition
Essential Tremor
Intervention / Treatment

-

Contacts and Locations

Gainesville

UF Health at the University of Florida, Gainesville, Florida, United States, 32610

Gainesville

McKnight Brain Institute--Fixel Center for Neurological Diseases, Gainesville, Florida, United States, 32611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Existing unilateral or bilateral VIN DBS for ET, non-demented (MMSE\>24), and must have a documented suboptimal tremor suppression on two successive visits (compared to the baseline post-operative improvement at 6 months following ET DBS surgery). For bilateral cases, the most affected tremor side will be studied.
  • * No diagnosis of Essential Tremor

Ages Eligible for Study

18 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Florida,

Leonardo B Almeida, MD, PRINCIPAL_INVESTIGATOR, Univeristy of Florida

Study Record Dates

2025-06-30