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Physiology, Imaging and Modeling of Essential Tremor

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Conditions

Essential TremorParkinson DiseaseDystoniaDeep Brain Stimulation (DBS)ventralis intermedius nucleus (VIN)implantable pulse generator (IPG)Diffusion Tensor Imaging (DTI)

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This project aims to investigate novel ways to deliver brain stimulation to Essential Tremor (ET) patients by introducing software changes to their existing devices. The study team aims to investigate safety and efficacy of these new stimulation parameters in patients with ET.

Official Title

Physiology, Imaging and Modeling of Deep Brain Stimulation for Essential Tremor

Quick Facts

Study Start:2021-04-01
Study Completion:2025-06-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT03811405

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Existing unilateral or bilateral VIN DBS for ET, non-demented (MMSE\>24), and must have a documented suboptimal tremor suppression on two successive visits (compared to the baseline post-operative improvement at 6 months following ET DBS surgery). For bilateral cases, the most affected tremor side will be studied.
  1. * No diagnosis of Essential Tremor

Contacts and Locations

Principal Investigator

Joshua K Wong, MD
PRINCIPAL_INVESTIGATOR
Univeristy of Florida

Study Locations (Sites)

UF Health at the University of Florida
Gainesville, Florida, 32610
United States
McKnight Brain Institute--Fixel Center for Neurological Diseases
Gainesville, Florida, 32611
United States

Collaborators and Investigators

Sponsor: University of Florida

  • Joshua K Wong, MD, PRINCIPAL_INVESTIGATOR, Univeristy of Florida

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-04-01
Study Completion Date2025-06-01

Study Record Updates

Study Start Date2021-04-01
Study Completion Date2025-06-01

Terms related to this study

Keywords Provided by Researchers

  • Deep Brain Stimulation (DBS)
  • ventralis intermedius nucleus (VIN)
  • implantable pulse generator (IPG)
  • Diffusion Tensor Imaging (DTI)

Additional Relevant MeSH Terms

  • Essential Tremor
  • Parkinson Disease
  • Dystonia