RECRUITING

Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for SAH

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Given the severe consequences of alcohol relapse following liver transplantation for alcoholic hepatitis (AH-LT), it is critical to accurately identify alcohol use and implement alcohol interventions early in the post-transplant period to optimize patient outcomes. The proposed randomized clinical trial will examine the implementation and effects of integrated, person- and computer-delivered alcohol treatment compared to standard care on alcohol use (assessed by self-report and biomarker), mood, quality of life and survival following AH-LT. Predictors of 12-month post-transplant alcohol outcomes will be explored to allow future improved tailoring and targeting of these treatments.

Official Title

Alcohol Treatment Outcomes Following Early vs. Standard Liver Transplant for Severe Alcoholic Hepatitis (SAH)

Quick Facts

Study Start:2020-11-20
Study Completion:2025-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03845205

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * English speaking
  1. * too medically/psychiatrically ill to participate
  2. * not able to provide informed consent due to cognitive impairment

Contacts and Locations

Study Contact

MARY E MCCAUL, PhD
CONTACT
410-955-9526
mmccaul1@jhmi.edu
Victor Chen, MD
CONTACT
410-550-1793
pchen37@jhmi.edu

Principal Investigator

Mary E McCaul, PhD
PRINCIPAL_INVESTIGATOR
Johns Hopkins University

Study Locations (Sites)

Johns Hopkins University School of Medicine
Baltimore, Maryland, 21205
United States

Collaborators and Investigators

Sponsor: Johns Hopkins University

  • Mary E McCaul, PhD, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-11-20
Study Completion Date2025-06

Study Record Updates

Study Start Date2020-11-20
Study Completion Date2025-06

Terms related to this study

Keywords Provided by Researchers

  • Alcohol treatment
  • Liver transplant
  • Motivational intervention
  • Cognitive-behavioral therapy

Additional Relevant MeSH Terms

  • Alcohol Use Disorder
  • Alcoholic Hepatitis