Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine

Description

This study will investigate if an intra-nasal nose spray of the drug oxytocin can decrease the amount of pressure needed from the automatic Continuous Positive Airway Pressure (CPAP) device while sleeping decreasing some of the harmful effects of low oxygen in people with sleep apnea. This study will last 35 nights and involves spending three nights in the sleep lab at George Washington University. There are no additional costs to participants and no compensation for being involved in the study.

Conditions

Sleep Apnea, Sleep Apnea, Obstructive

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Study Overview

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Study Details

Study overview

This study will investigate if an intra-nasal nose spray of the drug oxytocin can decrease the amount of pressure needed from the automatic Continuous Positive Airway Pressure (CPAP) device while sleeping decreasing some of the harmful effects of low oxygen in people with sleep apnea. This study will last 35 nights and involves spending three nights in the sleep lab at George Washington University. There are no additional costs to participants and no compensation for being involved in the study.

Benefits of Oxytocin in OSA Patients Using CPAP

Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine

Condition
Sleep Apnea
Intervention / Treatment

-

Contacts and Locations

Washington

Medical Faculty Associates, Washington, District of Columbia, United States, 20037

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Men or women 18 years of age or older.
  • * subjects not willing to or otherwise unable to use CPAP for treatment of OSA.
  • * Presence of other sleep disorders
  • * Pregnant or breastfeeding women
  • * Women of child-bearing age (WOCBA) not willing or unable to use an accepted method to avoid pregnancy for the entire duration of the study
  • * Prisoners or subjects who are involuntarily incarcerated
  • * Subjects who are compulsorily detain or treatment of either a psychiatric or physical (i.e. infectious disease) illness
  • * Patients unable to give consent because of a language barrier, or other reason.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Vivek Jain,

Vivek Jain, MD, PRINCIPAL_INVESTIGATOR, George Washington University

David Mendelowitz, PhD, PRINCIPAL_INVESTIGATOR, George Washington University

Study Record Dates

2024-11-01