The objective of this project is to compare chemosensitivity between chemotherapy combinations in bone marrow aspirates using 3D organoid models. The investigators overarching hypothesis is that 3D organoids are ideal to test chemosensitivity in real time, to provide personalized medicine and guidance in the setting of relapsed hematologic malignancy and potentially other cancers.
Hematologic Malignancy
The objective of this project is to compare chemosensitivity between chemotherapy combinations in bone marrow aspirates using 3D organoid models. The investigators overarching hypothesis is that 3D organoids are ideal to test chemosensitivity in real time, to provide personalized medicine and guidance in the setting of relapsed hematologic malignancy and potentially other cancers.
Novel 3D Hematological Malignancy Organoid to Study Disease Biology and Chemosensitivity
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Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina, United States, 27157
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
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18 Years to
ALL
No
Wake Forest University Health Sciences,
Timothy Pardee, MD, PhD, PRINCIPAL_INVESTIGATOR, Wake Forest University Health Sciences
2025-02