Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery

Description

Apply CT angiography, CT perfusion imaging and advanced image processing techniques to improve revascularization decision-making and surgical strategies in patients undergoing coronary artery bypass graft surgery.

Conditions

CAD, Atheroscleroses, Coronary, Computed Tomography, Coronary Artery Bypass

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Study Overview

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Study Details

Study overview

Apply CT angiography, CT perfusion imaging and advanced image processing techniques to improve revascularization decision-making and surgical strategies in patients undergoing coronary artery bypass graft surgery.

Comprehensive CT Guided Coronary Bypass Graft Surgery

Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery

Condition
CAD
Intervention / Treatment

-

Contacts and Locations

Palo Alto

Palo Alto Veterans Affaird Healthcare System, Palo Alto, California, United States, 94304

Palo Alto

Stanford University, Palo Alto, California, United States, 94304

San Diego

University of California San Diego, San Diego, California, United States, 92093

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Planned elective CABG for coronary artery disease.
  • * CABG is the primary indication for surgery (but may include treatment of mild-moderate valvular disease).
  • * Age: ≥40 years.
  • * Technical feasibility of the cardiac CT exams: redo-CABG, significant arrhythmia/mal-conduction, congenital conditions, severe valvular disease or cardiomyopathy (to the extent that the CT acquisition is technically challenged), inadequate understanding of the English language (to provide consent or follow instructions during the exams).
  • * Overall safety: unstable clinical condition (clinical heart failure, unstable angina, myocardial infarction \<1 month prior).
  • * Radiation risk: pregnancy (cannot be ruled out), body weight \>100kg.
  • * CT contrast medium-related: known allergy, renal failure
  • * Vasodilator related: known allergy, bronchial asthma requiring daily use of bronchodilators, Mobitz II or 3rd degree AV block, sick sinus node disease, clinically significant carotid artery narrowing, severe aortic stenosis or LVOT narrowing, systolic blood pressure below 90mmHg, (continued) use of dipyridamole or aminophylline.
  • * Inability to provide informed consent.

Ages Eligible for Study

40 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Stanford University,

Koen Nieman, MD, PhD, PRINCIPAL_INVESTIGATOR, Stanford University

Study Record Dates

2026-01