Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures

Description

The purpose of this investigation is to compare functional outcome measures and range of motion for patients receiving glucocorticoid (GC) injections versus those not receiving GCs for the treatment of distal radius fractures. The investigators hypothesize that patients who receive GC will have improved ROM and functional outcome measures compared to patients who do not receive GC. In addition, this study aims to determine if there is a difference in rates of complications and postoperative pain control between the GC and non-GC groups. In order to accomplish these aims, the investigators will conduct a prospective, randomized, controlled investigation.

Conditions

Distal Radius Fracture

Study Overview

Study Details

Study overview

The purpose of this investigation is to compare functional outcome measures and range of motion for patients receiving glucocorticoid (GC) injections versus those not receiving GCs for the treatment of distal radius fractures. The investigators hypothesize that patients who receive GC will have improved ROM and functional outcome measures compared to patients who do not receive GC. In addition, this study aims to determine if there is a difference in rates of complications and postoperative pain control between the GC and non-GC groups. In order to accomplish these aims, the investigators will conduct a prospective, randomized, controlled investigation.

The Effect on Wrist Range of Motion With Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures: A Randomized Controlled Trial

Perioperative Glucocorticoid Administration in the Treatment of Adult Distal Radius Fractures

Condition
Distal Radius Fracture
Intervention / Treatment

-

Contacts and Locations

Danville

Geisinger Woodbine, Danville, Pennsylvania, United States, 17821

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patient 18 years of age and older.
  • * Patients undergoing ORIF with VP fixation of an acute, isolated DRF with or without associated distal ulna fracture and with or without associated carpal tunnel release
  • * Worker's compensation patient
  • * Non-operatively treated fractures
  • * Open fractures
  • * Preoperative neurovascular injury
  • * Coexisting fractures or injuries
  • * Diabetes mellitus
  • * Allergy or contraindication to GCs
  • * Associated non-orthopedic injury that would prohibit the administration of GCs
  • * Patients currently incarcerated
  • * Pregnant patients

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

C. Liam Dwyer,

Liam Dwyer, MD, PRINCIPAL_INVESTIGATOR, Geisinger Clinic

Study Record Dates

2024-12