Bupivacaine/Epinephrine +Dexamethasone vs. Liposomal Bupivacaine

Description

This study will assess analgesia after robotic lung surgery. Subjects will be randomized to receive wound infiltration and intercostal nerve block with either liposomal bupivacaine or bupivacaine/epinephrine + dexamethasone. Liposomal bupivacaine is a newer local anesthetic product and has not been compared to a combination of bupivacaine/epinephrine + dexamethasone in the context of pain control after robotic lung surgery.

Conditions

Robotic Lung Surgery

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Study Overview

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Study Details

Study overview

This study will assess analgesia after robotic lung surgery. Subjects will be randomized to receive wound infiltration and intercostal nerve block with either liposomal bupivacaine or bupivacaine/epinephrine + dexamethasone. Liposomal bupivacaine is a newer local anesthetic product and has not been compared to a combination of bupivacaine/epinephrine + dexamethasone in the context of pain control after robotic lung surgery.

Title of Project: Liposomal Bupivacaine (Exparel) Versus Bupivacaine And Dexamethasone Intercostal Nerve Blocks For Robotic Thoracic Surgery: A Prospective Randomized Single-Blinded Clinical Trial

Bupivacaine/Epinephrine +Dexamethasone vs. Liposomal Bupivacaine

Condition
Robotic Lung Surgery
Intervention / Treatment

-

Contacts and Locations

Camden

Cooper University Hospital, Camden, New Jersey, United States, 08103

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * undergoing robotic wedge resection or lobectomy for lung mass(es)
  • * emergency case
  • * history of opiate abuse
  • * chronic pain syndrome
  • * intravenous drug use
  • * chronic use of oral steroids
  • * pregnancy
  • * imprisonment
  • * body weight lower than 70 kg
  • * liver failure
  • * uninsured patients
  • * non-verbal patients or patients who are unable to rate their pain on a visual analogue pain scale
  • * history of allergic reaction to any of the drugs used in the study: bupivacaine, liposomal bupivacaine, dexamethasone

Ages Eligible for Study

18 Years to 90 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

The Cooper Health System,

Study Record Dates

2022-06-10