Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

Description

The objective of this study is to better understand the comprehensive integration of both clinical and genetic factors that will help to identify mothers who could be at an increased risk of poor response to opioid substitution and infants at risk of significant neonatal abstinence syndrome (NAS).

Conditions

Opioid-use Disorder, Opioid Use, Unspecified, Buprenorphine Dependence

Study Overview

Study Details

Study overview

The objective of this study is to better understand the comprehensive integration of both clinical and genetic factors that will help to identify mothers who could be at an increased risk of poor response to opioid substitution and infants at risk of significant neonatal abstinence syndrome (NAS).

Effects of Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

Condition
Opioid-use Disorder
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

UPMC Children's Hospital, Pittsburgh, Pennsylvania, United States, 15224

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age greater 18 years
  • * Currently taking Buprenorphine for Opioid Use Disorder and enrolled in a prenatal opioid maintenance program in the antenatal clinic at IU Health University Hospital.
  • * Pregnant with single baby
  • * Planned delivery at Methodist, University or Riley Hospital
  • * Serious maternal medical illness as deemed by study physician or investigator.
  • * Known or suspected major fetal/neonatal congenital abnormalities.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Senthil Sadhasivam,

Senthil Sadhasivam, MD, MPH, PRINCIPAL_INVESTIGATOR, University of Pittsburgh, UPMC

Study Record Dates

2025-12-30