RECRUITING

Treatment Outcomes With tDCS in Post-Stroke Aphasia

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose this study is to test the utility of pairing external neuromodulation with behavioral language treatment to boost therapy outcomes and to investigate the mechanisms associated with recovery. Because all PWA have word retrieval deficits, this project will test if greater language gains can be achieved by supplementing anomia intervention with excitatory brain stimulation to the left hemisphere and will evaluate associated functional brain changes to aid the optimization of neural reorganization to facilitate language processing.

Official Title

Treatment Outcomes and Brain Mechanisms Associated With Non-Invasive Neuromodulation in Post-Stroke Aphasia

Quick Facts

Study Start:2019-09-03
Study Completion:2027-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03929432

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Presence of post-stroke aphasia
  2. * Single left hemisphere stroke etiology
  3. * At least 6 months post-stroke
  4. * Age range between 18 and 80 years old
  5. * Speak English as a native language
  6. * Adequate hearing and vision to complete the tasks
  1. * Severe auditory comprehension deficits (determined by pretest) (i.e., global aphasia, Wernicke's aphasia, transcortical sensory aphasia)
  2. * Inability to provide informed consent
  3. * Co-occurring history of neurological disease/disorder/injury (e.g., traumatic brain injury, right hemisphere stroke, dementia)
  4. * Co-occurring history of a major mental illness (e.g., schizophrenia, drug addiction, bipolar)
  5. * Clinical conditions contraindicated for MRI or tDCS (e.g., implanted electrical devices, claustrophobia, seizure disorder)
  6. * Positive pregnancy test (for females)

Contacts and Locations

Study Contact

Dana Moser, PhD, CCC-SLP
CONTACT
501-569-8914
DRMoser@uams.edu
Portia Carr
CONTACT
501-569-3155
PSCarr@uams.edu

Principal Investigator

Dana Moser, PhD, CCC-SLP
PRINCIPAL_INVESTIGATOR
University of Arkansas

Study Locations (Sites)

University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205
United States

Collaborators and Investigators

Sponsor: University of Arkansas

  • Dana Moser, PhD, CCC-SLP, PRINCIPAL_INVESTIGATOR, University of Arkansas

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-09-03
Study Completion Date2027-12

Study Record Updates

Study Start Date2019-09-03
Study Completion Date2027-12

Terms related to this study

Additional Relevant MeSH Terms

  • Aphasia