RECRUITING

Mobile Health Intervention to Support Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a small-scale micro-randomized clinical trial of a new mobile just-in-time adaptive intervention (JITAI) designed to promote oral chemotherapy adherence in adolescents and young adults (AYA) with acute lymphoblastic leukemia (ALL). The goals of this study are to determine intervention feasibility and acceptability.

Official Title

Using Real Time Mobile Health Approaches to Understand and Promote Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia

Quick Facts

Study Start:2025-07-30
Study Completion:2026-08-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03932903

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:14 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Ages 14-29
  2. * Diagnosed with acute lymphoblastic leukemia (ALL) or lymphoma
  3. * In the maintenance phase, completed at least one cycle and has at least one month of maintenance therapy remaining.
  4. * Prescribed 6-mercaptopurine (6MP)
  5. * English language proficiency
  6. * For AYA \<18, must have informed consent from their caregiver.
  1. * Cognitive impairments that would limit ability to complete measures, determined by the medical team
  2. * Absence of inclusion criteria above.

Contacts and Locations

Study Contact

Alexandra M Psihogios, Ph.D.
CONTACT
312-503-3577
alex.psihogios@northwestern.edu

Principal Investigator

Alexandra M Psihogios, Ph.D.
PRINCIPAL_INVESTIGATOR
Northwestern University

Study Locations (Sites)

Robert H. Lurie Comprehensive Cancer Center, Northwestern University
Chicago, Illinois, 60611
United States

Collaborators and Investigators

Sponsor: Northwestern University

  • Alexandra M Psihogios, Ph.D., PRINCIPAL_INVESTIGATOR, Northwestern University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-30
Study Completion Date2026-08-31

Study Record Updates

Study Start Date2025-07-30
Study Completion Date2026-08-31

Terms related to this study

Keywords Provided by Researchers

  • Adherence
  • Adolescent
  • Young Adult
  • Mobile Health
  • Oncology

Additional Relevant MeSH Terms

  • Acute Lymphoblastic Leukemia
  • Lymphoblastic Lymphoma