Smoking Cessation Behavioral Treatment Study

Description

The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT). MORE is a behavioral therapy that integrates mindfulness training to modify reward processes. CBT is a therapy designed to help individuals understand how their thoughts and feelings influence their behaviors.

Conditions

Tobacco Use Disorder

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Study Overview

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Study Details

Study overview

The purpose of this study is to evaluate the effectiveness of two behavioral interventions on smoking behavior - Mindfulness-Oriented Recovery Enhancement (MORE) and Cognitive Behavioral Therapy (CBT). MORE is a behavioral therapy that integrates mindfulness training to modify reward processes. CBT is a therapy designed to help individuals understand how their thoughts and feelings influence their behaviors.

Neural Mechanisms Mediating Appetitive Regulation and Smoking in Nicotine Addiction

Smoking Cessation Behavioral Treatment Study

Condition
Tobacco Use Disorder
Intervention / Treatment

-

Contacts and Locations

Columbia

University of Missouri - Columbia, Columbia, Missouri, United States, 65211

Charleston

Medical University of South Carolina, Charleston, South Carolina, United States, 29425

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18 and up
  • * English fluency as demonstrated in providing informed consent and the ability to independently follow directions in completing assigned assessments and tasks
  • * Functional vision (with corrective lenses as needed) to complete assigned assessments and tasks
  • * Current nicotine dependent smoker with a minimum smoking history of 2 years
  • * Interest in quitting smoking
  • * Use of psychotropic (e.g. antiepileptic) medications in the past month
  • * Positive urine drug screen
  • * Presence of an untreated medical illness
  • * Current or past psychosis
  • * History of major neurological illness or head injury resulting in loss of consciousness
  • * And contraindication to MRI, including claustrophobia
  • * Among females, positive urine pregnancy test
  • * Inability or unwillingness of subject to give informed consent

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Missouri-Columbia,

Study Record Dates

2025-03-31