Improving Bowel Function and Quality of Life After Spinal Cord Injury

Description

Bowel dysfunction is consistently rated as one of the most common complications affecting daily life for individuals with spinal cord injury. The overall objective of this study is to investigate whether the use of specific spinal cord epidural stimulation will affect bowel function. This study will also examine how alterations in bowel function influence quality of life outcomes. The results of this study may aid in the development of treatments to help individuals with spinal cord injuries that have impaired bowel function.

Conditions

Neurogenic Bowel

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Study Overview

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Study Details

Study overview

Bowel dysfunction is consistently rated as one of the most common complications affecting daily life for individuals with spinal cord injury. The overall objective of this study is to investigate whether the use of specific spinal cord epidural stimulation will affect bowel function. This study will also examine how alterations in bowel function influence quality of life outcomes. The results of this study may aid in the development of treatments to help individuals with spinal cord injuries that have impaired bowel function.

Targeting Improvements in Bowel Function and Quality of Life Using Epidural Stimulation and Training After Severe Spinal Cord Injury

Improving Bowel Function and Quality of Life After Spinal Cord Injury

Condition
Neurogenic Bowel
Intervention / Treatment

-

Contacts and Locations

Louisville

Frazier Rehab Institute, Louisville, Kentucky, United States, 40202

Louisville

University of Louisville, Louisville, Kentucky, United States, 40202

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * At least 18 years of age at the time of enrollment
  • * At least 2 years post injury
  • * Non-progressive spinal cord injury
  • * Stable medical condition
  • * Unable to voluntarily move all joints of the legs
  • * Unable to stand independently
  • * Cardiovascular dysfunction including presence of persistent resting low blood pressures and/or symptoms of autonomic dysreflexia and/or orthostatic hypotension and/or dysregulation in response to postural changes and/or highly variable blood pressures in 24 hour period
  • * Bowel dysfunction as a result of spinal cord injury
  • * Ventilator dependent
  • * Untreated painful musculoskeletal dysfunction, unhealed fracture or pressure sore
  • * Untreated psychiatric disorder or ongoing drug abuse
  • * Colostomy bag
  • * Any implanted pump (i.e., baclofen pump, pain pump, etc)
  • * Cardiovascular or bowel dysfunction unrelated to SCI
  • * Ongoing nicotine use
  • * Pregnant at the time of enrollment or planning to become pregnant during the time course of the study

Ages Eligible for Study

18 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Louisville,

Study Record Dates

2024-12-15