Oxybutynin for Post-surgical Bladder Pain and Urgency

Description

Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.

Conditions

Overactive Bladder Syndrome, Neuropathic Bladder

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Study Overview

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Study Details

Study overview

Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.

Oxybutynin for Post-surgical Bladder Pain and Urgency

Oxybutynin for Post-surgical Bladder Pain and Urgency

Condition
Overactive Bladder Syndrome
Intervention / Treatment

-

Contacts and Locations

Sacramento

University of California Davis Medical Center (UCDMC), Sacramento, California, United States, 95817

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients who will undergo bladder surgery that requires an indwelling bladder catheter after surgery.
  • * Age Range: Four to 8 years of age are eligible for the study.
  • * Patients who have had prior bladder surgery.
  • * Patients who have neurologic disease that could impair bladder sensation.
  • * Patients who are already taking antimuscarinic or antispasmodic medications.
  • * Patients with glaucoma, any neurologic disease, dementia, impaired mentation or disorder of the central nervous system.
  • * Patients taking any medication that affects the central nervous system such as antidepressant, anxiolytic or antipsychotic medications.
  • * Less than four years of age cannot have the transdermal patch due to fixed dose. Over 8 years of age: less than 5% of our patients, who undergo this surgery, are over 8 years of age and is usually a rare adolescent. Data in an older cohort may confuse the results since they respond differently to bladder surgery due to larger incision and longer hospital stay with a catheter.

Ages Eligible for Study

4 Years to 8 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of California, Davis,

Eric A Kurzrock, MD, PRINCIPAL_INVESTIGATOR, UC Davis Health Center

Study Record Dates

2025-12-31