Pulmonary Hemodynamics During Exercise - Research Network

Description

The purpose of this Clinical Research Collaboration is to investigate the prognostic implications of pulmonary hemodynamics during exercise based on a large scale multi-centre approach by using retrospective and prospective analysis of hemodynamic data.

Conditions

Pulmonary Circulation Diseases

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Study Overview

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Study Details

Study overview

The purpose of this Clinical Research Collaboration is to investigate the prognostic implications of pulmonary hemodynamics during exercise based on a large scale multi-centre approach by using retrospective and prospective analysis of hemodynamic data.

Pulmonary Hemodynamics During Exercise - Research Network

Pulmonary Hemodynamics During Exercise - Research Network

Condition
Pulmonary Circulation Diseases
Intervention / Treatment

-

Contacts and Locations

Phoenix

University of Arizona, Banner University Medical Center, Phoenix, Arizona, United States, 85724

Los Angeles

University of California, Los Angeles, Lung & Heart-Lung Transplant and Pulmonary Hypertension Programs, David Geffen School of Medicine, Los Angeles, California, United States, 90095

Baltimore

Johns Hopkins Hospital, Advanced HF, MCS, Transplant Cardiology, Baltimore, Maryland, USA, Baltimore, Maryland, United States, 21287

Boston

Massachusetts General Hospital, Cardiology Division and Pulmonary Unit, Boston, Massachusetts, United States, 02114

Boston

Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, United States, 02138

Minneapolis

University of Minnesota Medical School, Division of Cardiology, Department of Medicine, Lillehei Heart Institute Minneapolis, Minnesota, USA, Minneapolis, Minnesota, United States, 55455

Rochester

Mayo Clinic, Division of Cardiovascular Diseases, Department of Medicine, Rochester, Minnesota, United States, 85259

Charleston

Medical University of South Carolina, Charleston, South Carolina, United States, 29425

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients (females and males; age: above 18yrs) with intermediate or high echocardiographic probability of PH and/or unexplained dyspnea, and/or associated conditions for PAH as clinical indication for RHC at rest and exercise
  • * Written informed consent of participating subjects after being fully briefed (for prospective analysis)
  • * Patients with incomplete hemodynamic data at rest or exercise
  • * Patients without sufficient follow-up data (information on survival / lung transplantation)
  • * advanced tumour disease or other diseases with a short life expectancy, except pulmonary vascular diseases
  • * advanced heart failure with pulmonary arterial wedge pressure (PAWP) \> 18 mmHg at rest
  • * uncontrolled systemic arterial hypertension (RR values \> 160/100 mmHg at rest)
  • * FEV1\<50% predicted
  • * TLC\<60% predicted

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Medical University of Graz,

Horst Olschewski, MD, STUDY_CHAIR, Medical University of Graz

Philippe Herve, MD, STUDY_CHAIR, Centre Chirugical Marie Lannelongue

Study Record Dates

2029-12-31