RECRUITING

The Validity of the Quick Renal MRI in Pediatric Kidney Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators propose a new imaging method for children born with congenital anomalies of the urinary tract that is a rapid, injection-, sedation-, and radiation-free alternative: the quick renal MRI. This proposal hypothesizes that the quick renal MRI has high validity compared to current radiologic standard for renal infection and scarring, the 99mTechnetium-dimercaptosuccinic acid (99mTc- DMSA) renal scan in the detection of acute renal infections and scars. If the quick renal MRI is accurate, it could potentially replace the DMSA scan for those specific questions and ease the burden of testing for children with chronic renal disease. Findings from these studies will provide preliminary data and rationale for a multi-centered study to further test this new technology. Participants will be 0-21 years of age and can expect to be on study for from 1 week (if enrolled in Aim 1) to 6 months (if enrolled in Aim 2).

Official Title

The Validity of the Quick Renal MRI in Pediatric Kidney Disease

Quick Facts

Study Start:2019-05-07
Study Completion:2025-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03959163

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:0 Years to 21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Aim 1:
  2. * Patient is admitted to American Family Children's Hospital for a febrile UTI, suspected pyelonephritis, or diagnosed pyelonephritis
  3. * Undergoing clinical DMSA scan
  4. * Aim 2:
  5. * Undergoing DMSA scans as a part of their routine clinical care
  6. * History of more than one UTI in the past year
  1. * Aim 1:
  2. * No evidence of pyuria on their urine analysis
  3. * Negative urine culture
  4. * Not comfortable with having a Quick MRI performed
  5. * Both aims:
  6. * Contraindications to MRI

Contacts and Locations

Study Contact

Shannon Cannon, MD
CONTACT
(608) 265-8574
cannon@urology.wisc.edu

Principal Investigator

Shannon Cannon, MD
PRINCIPAL_INVESTIGATOR
University of Wisconsin, Madison

Study Locations (Sites)

American Family Children's Hospital
Madison, Wisconsin, 53792
United States

Collaborators and Investigators

Sponsor: University of Wisconsin, Madison

  • Shannon Cannon, MD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-05-07
Study Completion Date2025-01

Study Record Updates

Study Start Date2019-05-07
Study Completion Date2025-01

Terms related to this study

Additional Relevant MeSH Terms

  • Pyelonephritis
  • Pyelonephritis Acute
  • Renal Sclerosis