ACTIVE_NOT_RECRUITING

Snapshot Camera for AMD

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study proposes to use a new instrument (AO-OCT/AF: adaptive optics - optical coherence tomography/autofluorescence) combined with a data processing method to image the retinal pigment epithelium (RPE) of the eye in normal subjects and in subjects with age-related macular degeneration. (AMD). While currently there is no cure, with early diagnosis, vision loss can be slowed. The technology being developed for this project will be the first imaging modality that can provide both structural and molecular information about the retina in vivo and in 3D.

Official Title

Snapshot 3D Ultra-high-resolution OCT and Hyperspectral AF of In-vivo Retina

Quick Facts

Study Start:2023-09-06
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT03963817

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients must be aged 60 and over and pseudophakic, with clear posterior capsule and dilation to 6mm.
  2. * Patients must be diagnosed early/intermediate AMD in at least one eye (the study eye) with soft drusen or reticular pseudodrusen in the macula.
  1. * Retinopathy other than AMD.
  2. * Inability to give informed consent
  3. * Bilateral advanced AMD
  4. * Allergy to dilation eye drops

Contacts and Locations

Principal Investigator

Ronald Theodore Smith, MD, PhD
PRINCIPAL_INVESTIGATOR
Icahn School of Medicine at Mount Sinai

Study Locations (Sites)

New York Eye and Ear Infirmary of Mount Sinai
New York, New York, 10003
United States

Collaborators and Investigators

Sponsor: Icahn School of Medicine at Mount Sinai

  • Ronald Theodore Smith, MD, PhD, PRINCIPAL_INVESTIGATOR, Icahn School of Medicine at Mount Sinai

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-09-06
Study Completion Date2025-12

Study Record Updates

Study Start Date2023-09-06
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • Imaging
  • Autofluorescence imaging
  • Spectral domain optical coherence tomography
  • Adaptive optics
  • Soft drusen
  • Reticular pseudodrusen

Additional Relevant MeSH Terms

  • Age Related Macular Degeneration