COMPLETED

Role of the Sympathetic Nervous System in Rosacea

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Rosacea is a common skin disorder which causes facial redness and inflammation in about 16 million Americans, from an unknown cause. Many triggers of rosacea symptoms are stressors that affect the sympathetic ("fight or flight") portion of the nervous system, and a recent pilot study suggests there is sympathetic dysfunction in rosacea. This project will benefit patients, clinicians, and basic scientists by increasing our understanding of sympathetic nervous system involvement in rosacea symptoms in order to develop improved treatments for patients with rosacea.

Official Title

Role of the Sympathetic Nervous System in Rosacea

Quick Facts

Study Start:2019-05-24
Study Completion:2020-08-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT03989492

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 45 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Otherwise healthy males and non-pregnant/non-lactating females with mild to moderate erythematotelangiectactic rosacea, as well as age-sex matched healthy control subjects.
  1. * Neurological, cardiovascular, respiratory, metabolic, muscular, or other dermatological disorders
  2. * Current history of alcohol and/or drug abuse
  3. * Known allergies or hypersensitivities to medications/drugs that are used in the protocol
  4. * Current smoking or regular smoking within the last 2 years
  5. * Body mass index \> 35 kg/m2
  6. * Medications or supplements which are known to affect neural, cardiovascular, or muscular responses

Contacts and Locations

Principal Investigator

Kristen Metzler-Wilson, PT, PhD
PRINCIPAL_INVESTIGATOR
University of Kentucky

Study Locations (Sites)

Indiana University
Indianapolis, Indiana, 46202
United States
University of Kentucky
Lexington, Kentucky, 40506
United States

Collaborators and Investigators

Sponsor: Kristen Metzler-Wilson

  • Kristen Metzler-Wilson, PT, PhD, PRINCIPAL_INVESTIGATOR, University of Kentucky

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-05-24
Study Completion Date2020-08-06

Study Record Updates

Study Start Date2019-05-24
Study Completion Date2020-08-06

Terms related to this study

Keywords Provided by Researchers

  • autonomic nervous system
  • skin blood flow
  • skin sympathetic nerve activity

Additional Relevant MeSH Terms

  • Rosacea