Pilot Study of BCAA on Sleep

Description

Individuals will be recruited from the VA Portland Health Care System and the community affiliated with Oregon Health \& Science University. Traumatic brain injury status will be assessed as a contributing factor. Subjects will be randomized to one of 3 groups (BCAA or one of 2 placebo conditions) and instructed to consume study product twice daily for 21 days. Self-report questionnaires, wrist actigraphy, pressure pain testing, and cognitive function will be assessed pre and post the experimental period.

Conditions

Sleep Disorder, Traumatic Brain Injury

Study Overview

Study Details

Study overview

Individuals will be recruited from the VA Portland Health Care System and the community affiliated with Oregon Health \& Science University. Traumatic brain injury status will be assessed as a contributing factor. Subjects will be randomized to one of 3 groups (BCAA or one of 2 placebo conditions) and instructed to consume study product twice daily for 21 days. Self-report questionnaires, wrist actigraphy, pressure pain testing, and cognitive function will be assessed pre and post the experimental period.

A Pilot Study of Dietary Supplementation With Branched Chain Amino Acids on Sleep

Pilot Study of BCAA on Sleep

Condition
Sleep Disorder
Intervention / Treatment

-

Contacts and Locations

Portland

VA Portland Health Care System, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Veteran
  • * English Speaking
  • * Accessible via phone
  • * Sleep problems
  • * Decisional impairment
  • * Nickel allergy
  • * Maple syrup urine disease or family history of disease
  • * Allergy to sucralose
  • * Currently taking BCAAs

Ages Eligible for Study

18 Years to 89 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Portland VA Medical Center,

Miranda M Lim, MD, PhD, PRINCIPAL_INVESTIGATOR, Portland VA Medical Center

Study Record Dates

2025-08-01