S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion

Description

The Purpose of the study is to test the hypothesis that administration of an S-nitrosylating (SNO) agent can improve tissue oxygenation during transfusion of packed red blood cells (RBCs).

Conditions

Transfusion Related Complication

Study Overview

Study Details

Study overview

The Purpose of the study is to test the hypothesis that administration of an S-nitrosylating (SNO) agent can improve tissue oxygenation during transfusion of packed red blood cells (RBCs).

Phase 1 Study of S-Nitrosylation Therapy to Improve Tissue Oxygenation During Autologous Blood Transfusion in Healthy Volunteer

S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion

Condition
Transfusion Related Complication
Intervention / Treatment

-

Contacts and Locations

Cleveland

University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States, 44106

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to 35 Years

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    Yes

    Collaborators and Investigators

    James Reynolds,

    Mada Helou, MD, PRINCIPAL_INVESTIGATOR, University Hospitals Cleveland Medical Center

    Batuhan Degis, MD, STUDY_DIRECTOR, Case Western Reserve University

    Study Record Dates

    2028-02-29