RECRUITING

A Post-Market Clinical Evaluation of the Treatment of Femur Fractures With the Femoral Nail PF

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This investigation is a prospective, multicenter clinical investigation. It is anticipated that a total of 50 subjects will be enrolled at up to 5 sites. Enrollment is estimated to commence in Q4 of 2018. Neither subjects nor investigators are blinded to treatment and the clinical investigation includes a historical control which will be compared to the Femoral Nail PF of the T2 Alpha Femur Antegrade GT/PF Nailing System. Total duration of enrollment, 12 month follow-up and analysis is expected to take 29 months. The clinical investigation has been designed to follow the surgeon's standard of care for femur fractured subjects, in addition to a 12 month follow-up visit. The primary endpoint of this clinical investigation is to confirm efficacy/performance at 12 months, as measured by the Lower Extremity Measure (LEM). Confirmation of efficacy/performance at 12 months will be based on an equal or greater (non-inferior) LEM score result of the Femoral Nail PF of the T2 Alpha Femur Antegrade GT/PF Nailing System compared to the T2 Femur benchmark literature.

Official Title

A Post-Market Clinical Evaluation of the Treatment of Femur Fractures With the Femoral Nail Piriformis Fossa (PF) of the T2 Alpha Femur Antegrade GT/PF Nailing System

Quick Facts

Study Start:2019-09-12
Study Completion:2025-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04015154

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Subject is a male or non-pregnant female age 18 years or older at the time of surgery;
  2. * Subject is willing and able to give written informed consent and comply with the requirements of this Clinical Investigation Plan;
  3. * Subject is intended to be treated with the Femoral Nail PF of the T2 Alpha Femur Antegrade GT/PF Nailing System in accordance with the following legally cleared/ approved Indications for Use:
  4. * Fixation of subtrochanteric, intertrochanteric, ipsilateral neck/shaft, comminuted proximal femoral shaft fractures
  5. * Femoral fixation required as a result of pathological disease
  6. * Temporary stabilization of fractures of the femoral shaft ranging from the femoral neck to the supracondylar regions of the femur
  7. * Open and closed femoral fractures
  8. * Pseudoarthrosis and correction osteotomy
  9. * Pathologic fractures, impending pathologic fractures and tumor resections
  10. * Ipsilateral femur fractures
  11. * Fractures proximal to a total knee arthroplasty
  12. * Nonunions and malunions
  13. * Fractures involving osteopenic and osteoporotic bone
  1. * Subject is currently enrolled in or plans to enroll in any concurrent drug and/or device clinical investigation that, in the opinion of the Investigator, may confound results;
  2. * Per the Investigator, the subject is in poor general health or undergoing any concurrent disease that would place the subject in excessive risk to surgery (i.e. significant circulatory problems, cardiac disease).

Contacts and Locations

Study Contact

Monica Fleeman
CONTACT
251 465 5969
monica.fleeman@stryker.com
Jennifer Seidman
CONTACT
jennifer.seidman@stryker.com

Principal Investigator

Rebecca Gibson
STUDY_DIRECTOR
Stryker Trauma and Extremities

Study Locations (Sites)

St. Cloud Orthopedic Associates, Ltd
Sartell, Minnesota, 56377
United States
Reno Orthopedic Clinic
Reno, Nevada, 89503
United States
Ariana Meltzer-Bruhn
New York, New York, 10016
United States
UC Health
Cincinnati, Ohio, 45229
United States
Inova Fairfax Medical Campus
Falls Church, Virginia, 22042
United States

Collaborators and Investigators

Sponsor: Stryker Trauma and Extremities

  • Rebecca Gibson, STUDY_DIRECTOR, Stryker Trauma and Extremities

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-09-12
Study Completion Date2025-06

Study Record Updates

Study Start Date2019-09-12
Study Completion Date2025-06

Terms related to this study

Additional Relevant MeSH Terms

  • Femoral Fracture