COMPLETED

The Registry of Oncology Outcomes Associated with Testing and Treatment

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study is to collect and validate regulatory-grade real-world data (RWD) in oncology using the novel, Master Observational Trial construct. This data can be then used in real-world evidence (RWE) generation. It will also create reusable infrastructure to allow creation or affiliation with many additional RWD/RWE efforts both prospective and retrospective in nature.

Official Title

The Registry of Oncology Outcomes Associated with Testing and Treatment (ROOT)

Quick Facts

Study Start:2021-05-05
Study Completion:2024-10-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT04028479

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patient or representative provides written informed consent
  2. * Patient is diagnosed with advanced malignancy
  3. * Patient is willing to be treated for this malignancy according to a plan determine by them and their physician
  4. * patient will be willing to have regular follow up visits as part of their standard of care
  1. * patient is not a candidate or does not desire any treatment for their disease

Contacts and Locations

Principal Investigator

Razelle Kurzrock, MD
STUDY_CHAIR
Moores Cancer Center at University of California at San Diego
Vivek Subbiah, MD
PRINCIPAL_INVESTIGATOR
M.D. Anderson Cancer Center
Jennifer Johnson, MD, PhD
PRINCIPAL_INVESTIGATOR
Sidney Kimmel Cancer Center at Thomas Jefferson University
Raymond Bergan, MD
PRINCIPAL_INVESTIGATOR
OHSU Knight Cancer Institute

Study Locations (Sites)

Teton Cancer Institute
Idaho Falls, Idaho, 83404
United States
Oncology and Hematology of South Texas
Laredo, Texas, 78041
United States

Collaborators and Investigators

Sponsor: Taproot Health

  • Razelle Kurzrock, MD, STUDY_CHAIR, Moores Cancer Center at University of California at San Diego
  • Vivek Subbiah, MD, PRINCIPAL_INVESTIGATOR, M.D. Anderson Cancer Center
  • Jennifer Johnson, MD, PhD, PRINCIPAL_INVESTIGATOR, Sidney Kimmel Cancer Center at Thomas Jefferson University
  • Raymond Bergan, MD, PRINCIPAL_INVESTIGATOR, OHSU Knight Cancer Institute

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-05-05
Study Completion Date2024-10-31

Study Record Updates

Study Start Date2021-05-05
Study Completion Date2024-10-31

Terms related to this study

Keywords Provided by Researchers

  • Precision Medicine
  • Molecular Sequence Data
  • Databases, Genetic
  • High-Throughput Nucleotide Sequencing
  • Massively-Parallel Sequencing
  • Observational Study
  • Treatment
  • Patient Outcome Assessment
  • Adaptive clinical trial
  • Molecular Typing
  • Response Rate
  • Progression Free Survival
  • Overall Survival

Additional Relevant MeSH Terms

  • Adenocarcinoma
  • Adenocystic Carcinoma
  • Anal Cancer
  • Appendix Cancer
  • Brain Tumor
  • Glioblastoma
  • Astrocytoma
  • Bile Duct Cancer
  • Cholangiocarcinoma
  • Bladder Cancer
  • Bone Cancer
  • Synovial Sarcoma
  • Chondrosarcoma
  • Liposarcoma
  • Sarcoma, Kaposi
  • Sarcoma,Soft Tissue
  • Sarcoma
  • Osteosarcoma
  • CNS Cancer
  • Brain Stem Neoplasms
  • Breast Cancer
  • Cervical Cancer
  • Colorectal Cancer
  • Rectal Cancer
  • Colon Cancer
  • Esophageal Cancer
  • Esophagus Cancer
  • Cancer of Colon
  • Pancreatic Cancer
  • Cancer of Pancreas
  • Testis Cancer
  • Testicular Cancer
  • Ureter Cancer
  • Renal Cell Carcinoma
  • Kidney Cancer
  • Gestational Trophoblastic Tumor
  • Head and Neck Neoplasms
  • Parotid Tumor
  • Larynx Cancer
  • Tongue Cancer
  • Pharynx Cancer
  • Salivary Gland Cancer
  • Acute Myeloid Leukemia
  • Chronic Myeloid Leukemia
  • Acute Lymphoblastic Leukemia
  • Multiple Myeloma
  • Non Hodgkin Lymphoma
  • Carcinoid Tumor
  • Lung Cancer
  • Neuroendocrine Tumors
  • Mesothelioma
  • Thyroid Cancer
  • Parathyroid Neoplasms
  • Adrenal Cancer
  • Small Bowel Cancer
  • Stomach Cancer
  • Liver Cancer
  • Hepatic Cancer
  • Melanoma
  • Skin Cancer
  • Unknown Primary Tumors
  • Uterine Cancer
  • Fallopian Tube Cancer
  • Ovarian Cancer
  • Prostate Cancer
  • Vaginal Cancer
  • Penile Cancer
  • Vulvar Cancer
  • Waldenstrom Macroglobulinemia
  • Cancer, Advanced
  • Thymus Cancer
  • Nasopharyngeal Carcinoma
  • Multiple Endocrine Neoplasia
  • Pheochromocytoma
  • Small Cell Carcinoma
  • Pulmonary Carcinoma