Vicryl Rapide Versus Nonabsorbable Suture

Description

This will be a prospective, randomized controlled trial assessing noninferiority of Vicryl Rapide compared to nonabsorbable suture. The study will be conducted in the Community Regional Medical Center emergency department (ED). The aim of this study, then, is to prospectively determine if 3-month cosmesis for traumatic laceration repair of trunk/extremity lacerations in adult patients with Vicryl Rapide is noninferior to nonabsorbable suture.

Conditions

Traumatic Lacerations

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Study Overview

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Study Details

Study overview

This will be a prospective, randomized controlled trial assessing noninferiority of Vicryl Rapide compared to nonabsorbable suture. The study will be conducted in the Community Regional Medical Center emergency department (ED). The aim of this study, then, is to prospectively determine if 3-month cosmesis for traumatic laceration repair of trunk/extremity lacerations in adult patients with Vicryl Rapide is noninferior to nonabsorbable suture.

Vicryl Rapide Versus Nonabsorbable Suture in Repair of Simple Traumatic Extremity and Trunk Lacerations in Adult Patients

Vicryl Rapide Versus Nonabsorbable Suture

Condition
Traumatic Lacerations
Intervention / Treatment

-

Contacts and Locations

Fresno

Community Regional Medical Center, Fresno, California, United States, 93721

Fresno

Community Regional Trauma and Burn Center, Fresno, California, United States, 93721

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patient 18-years or older
  • * single laceration on trunk or extremity requiring suture closure
  • * laceration length \> 2-cm
  • * wound to be closed with simple interrupted sutures
  • * High infection potential
  • * Must have one of the following:
  • * puncture wound
  • * -highly contaminated
  • * devitalized tissue requiring sharp debridement
  • * -bite wounds
  • * -\> 24-hours-old
  • * Low likelihood of good cosmesis
  • * Must have one of the following:
  • * -wound
  • * -crush wound
  • * -soft tissue deficit limiting complete apposition of wound edges
  • * -significant overlying macerated/abraded tissue
  • * Underlying tendon or cartilage involvement
  • * Significant wound healing problems
  • * Must have one of the following:
  • * keloid formers
  • * chronic steroid use
  • * other: ______________________ -Inability to give written consent
  • * Must have one of the following:
  • * non-English or non-Spanish speaker
  • * altered mental status
  • * incarcerated patient
  • * No telephone number or unlikely to return for 3-month follow-up
  • * Must have one of the following:
  • * homeless
  • * psychiatric patient,
  • * nursing home patient,
  • * other: ______________________
  • * More than one laceration needing suture repair on trunk or extremity (i.e. appropriate to proceed if second laceration is to face/neck)

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of California, San Francisco,

Brian Chinnock, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

2026-01-31