Near Infrared Spectroscopy (NIRS) for Assessment of Depression

Description

Develop a NIRSIT testing protocol that can be administered in the diagnostic setting and reliably distinguishes the symptoms and severity of depression, with the help of repeated measure (up to five visits per subject) comparison of patients being treated for Major Depressive Disorder with control, non-depressed subjects.

Conditions

Major Depressive Disorder

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Study Overview

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Study Details

Study overview

Develop a NIRSIT testing protocol that can be administered in the diagnostic setting and reliably distinguishes the symptoms and severity of depression, with the help of repeated measure (up to five visits per subject) comparison of patients being treated for Major Depressive Disorder with control, non-depressed subjects.

Clinical Testing of Near Infrared Spectroscopy (NIRS) for Quantitative Assessment of Depression

Near Infrared Spectroscopy (NIRS) for Assessment of Depression

Condition
Major Depressive Disorder
Intervention / Treatment

-

Contacts and Locations

San Francisco

San Francisco Veterans Affairs Medical Center, San Francisco, California, United States, 94121

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * All subjects who sign informed consent.
  • * Controls: Volunteers over 18 years of age who are not depressed.
  • * Patients over 18 years of age with a diagnosis of Major Depressive Disorder, receiving clinical therapy at SFVAMC.
  • * Subjects who cannot sign informed consent.
  • * Exclusion criteria for control subjects: 1.Depression 2.Anxiety, psychotic, substance abuse, mood and personality disorders 3.Major neurocognitive disorders such as Alzheimer's disease and other dementias 4.Neurologic disorders with anatomic lesions including traumatic brain injury, stroke, tumor and arteriovenous malformation
  • * Exclusion criteria for depressed patients: 1.Psychotic disorders like schizophrenia 2.Major neurocognitive disorders such as Alzheimer's disease and other dementias 3.Neurologic disorders with anatomic lesions including traumatic brain injury, stroke, tumor and arteriovenous malformation 4.Not receiving clinical therapy for depression at SFVAMC'

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of California, San Francisco,

Arthur Wallace, MD, PhD, PRINCIPAL_INVESTIGATOR, San Francisco Veterans Affairs Medical Center

Study Record Dates

2026-12-30