ACTIVE_NOT_RECRUITING

TRAIN-BW: Backward Walking Training in Multiple Sclerosis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Individuals with multiple sclerosis (MS) experience in impairments in mobility and cognition that increase the risk for accidental falls. More than 50% of individuals with MS experience injurious falls within a 6-month period. Current interventions to improve fall risk have focused on forward walking (FW) and balance training, resulting in small declines in the relative risk for falls with a large degree of variability. Interestingly, motor differences between MS and healthy controls are more pronounced in backward walking (BW), yet no studies have investigated BW training as an intervention to reduce fall risk in persons with MS. This study will investigate the feasibility, acceptability and impact of BW training compared to forward walking training on motor function and fall risk in persons with MS.

Official Title

TRAIN-BW: Backward Walking Training in Multiple Sclerosis

Quick Facts

Study Start:2020-01-01
Study Completion:2026-02-28
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT04091464

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Diagnosis of MS
  2. * PDDS \<6, indicating ability to ambulate with or without an assistive device \>/= 50% of the time
  3. * Self-reported walking dysfunction as evidenced by a score of \>/= 30 on MSWS-12 OR reports of 2 or more falls in the prior 6 months, indicating a frequent faller.
  1. * MS relapse within the past 30 days
  2. * comorbid neurological disorder
  3. * acute orthopedic disorder/injury
  4. * unable to follow study-related commands

Contacts and Locations

Principal Investigator

Nora Fritz, PhD
PRINCIPAL_INVESTIGATOR
Wayne State University

Study Locations (Sites)

Wayne State University
Detroit, Michigan, 48201
United States

Collaborators and Investigators

Sponsor: Wayne State University

  • Nora Fritz, PhD, PRINCIPAL_INVESTIGATOR, Wayne State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-01-01
Study Completion Date2026-02-28

Study Record Updates

Study Start Date2020-01-01
Study Completion Date2026-02-28

Terms related to this study

Keywords Provided by Researchers

  • Backward Walking
  • Neurorehabilitation

Additional Relevant MeSH Terms

  • Multiple Sclerosis
  • Gait Disorders, Neurologic
  • Accidental Fall