RECRUITING

Enhanced Recovery After Surgery in Kidney Transplant Donors

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Enhanced recovery after surgery (ERAS) pathways are designed to optimize perioperative management, improving patient outcomes and satisfaction through multimodal techniques. Living kidney transplant donors are typically healthy individuals who undergo laparoscopic nephrectomy. The most significant hindrance to discharge to return to activities of daily living is frequently return of bowel function and postoperative pain. Through a randomized controlled trial design, we will evaluate the effectiveness of implementing an ERAS pathway. We hypothesize that preoperative patient optimization through exercise, carbohydrate loading, and counseling on expectations, in addition to multimodal pain management strategies which limit opioids would allow faster recovery, early bowel function, decreased postoperative pain, increased patient satisfaction and shorter length of stay. The study population will include a total of 42 patients (age 18-80) who are American Society of Anesthesiologists (ASA) Physical Status (PS) 1-3, undergoing living donor nephrectomy. Our primary outcome measures will be postoperative opioid consumption. Secondary outcome measures are: postoperative pain score, time to return of bowel function, ambulation, first oral intake postoperatively, and patient satisfaction scores. Other objectives include reducing readmissions, shorter hospital length of stay and decreased operative complications, including nausea, vomiting and wound infection.

Official Title

Enhanced Recovery After Surgery in Living Donor Kidney Transplant Donors

Quick Facts

Study Start:2019-09-12
Study Completion:2023-06-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04110080

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * All patients undergoing this procedure who consent
  1. * patient refusal, female patients who are pregnant or nursing, patients with allergy to local anesthetic, American Society of Anesthesiology classification greater than 3

Contacts and Locations

Study Contact

Natalie Neiswinter, MD
CONTACT
7176794438
natalie.neiswinter@jefferson.edu
Uzong Yoon, MD, MPH
CONTACT
215-955-6161
uzung.yoon@jefferson.edu

Principal Investigator

Uzong Yoon, MD, MPH
PRINCIPAL_INVESTIGATOR
Thomas Jefferson University

Study Locations (Sites)

Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19102
United States

Collaborators and Investigators

Sponsor: Thomas Jefferson University

  • Uzong Yoon, MD, MPH, PRINCIPAL_INVESTIGATOR, Thomas Jefferson University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-09-12
Study Completion Date2023-06-12

Study Record Updates

Study Start Date2019-09-12
Study Completion Date2023-06-12

Terms related to this study

Keywords Provided by Researchers

  • enhanced recovery after surgery
  • living donor kidney transplant
  • multimodal analgesia

Additional Relevant MeSH Terms

  • Opioid Use
  • Kidney Diseases
  • Pain, Postoperative
  • Postoperative Complications
  • Postoperative Nausea and Vomiting