RECRUITING

Comparative Imaging Assessment of Valvular Heart Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right ventricular systolic function strain and myocardial fibrosis assessment.

Official Title

Assessment of Left Ventricular Volumes and Strain and Assessment of Valvular Lesions Using Two- and Three-dimensional Echocardiography and Cardiac MRI, a Correlation Study

Quick Facts

Study Start:2019-08-23
Study Completion:2026-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04126018

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 18-90 years of age
  2. * Suspected moderate or severe MR,AR or AS on the basis of prior known clinical history or clinical exam.
  3. * Suspected CRT "non-responder" with an implanted MRI compatible CRT device and reduced ejection fraction
  1. * Acute traumatic cardiac injury
  2. * Aortic dissection or aortic root rupture
  3. * Congenital heart diseases such as patent ductus arteriosus, coarctation of aorta, ASD and VSD
  4. * Presence of A-V fistula or intracardiac shunts
  5. * Any contraindications to CMR
  6. * Moderate or severe dysfunction in multiple valves
  7. * Patients with significant claustrophobia

Contacts and Locations

Study Contact

Deborah Kwon, M. D.
CONTACT
216-444-8526
kwond@ccf.org

Principal Investigator

Deborah Kwon, M. D.
PRINCIPAL_INVESTIGATOR
The Cleveland Clinic

Study Locations (Sites)

Cleveland Clinic
Cleveland, Ohio, 44195
United States

Collaborators and Investigators

Sponsor: The Cleveland Clinic

  • Deborah Kwon, M. D., PRINCIPAL_INVESTIGATOR, The Cleveland Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-08-23
Study Completion Date2026-06-30

Study Record Updates

Study Start Date2019-08-23
Study Completion Date2026-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Valve Heart Disease
  • Aortic Stenosis
  • Aortic Regurgitation