Comparative Imaging Assessment of Valvular Heart Disease

Description

The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right ventricular systolic function strain and myocardial fibrosis assessment.

Conditions

Valve Heart Disease, Aortic Stenosis, Aortic Regurgitation

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Study Overview

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Study Details

Study overview

The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right ventricular systolic function strain and myocardial fibrosis assessment.

Assessment of Left Ventricular Volumes and Strain and Assessment of Valvular Lesions Using Two- and Three-dimensional Echocardiography and Cardiac MRI, a Correlation Study

Comparative Imaging Assessment of Valvular Heart Disease

Condition
Valve Heart Disease
Intervention / Treatment

-

Contacts and Locations

Cleveland

Cleveland Clinic, Cleveland, Ohio, United States, 44195

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18-90 years of age
  • * Suspected moderate or severe MR,AR or AS on the basis of prior known clinical history or clinical exam.
  • * Suspected CRT "non-responder" with an implanted MRI compatible CRT device and reduced ejection fraction
  • * Acute traumatic cardiac injury
  • * Aortic dissection or aortic root rupture
  • * Congenital heart diseases such as patent ductus arteriosus, coarctation of aorta, ASD and VSD
  • * Presence of A-V fistula or intracardiac shunts
  • * Any contraindications to CMR
  • * Moderate or severe dysfunction in multiple valves
  • * Patients with significant claustrophobia

Ages Eligible for Study

18 Years to 90 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

The Cleveland Clinic,

Deborah Kwon, M. D., PRINCIPAL_INVESTIGATOR, The Cleveland Clinic

Study Record Dates

2026-06-30