Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD

Description

The proposed randomized, double-blind research study will use functional magnetic resonance neuroimaging using state-of-the-art HCP acquisition protocols and analytic pipelines, to identify predictors and correlates of response to an accepted first-line pharmacological treatment for obsessive-compulsive disorder.

Conditions

Obsessive-Compulsive Disorder

Study Overview

Study Details

Study overview

The proposed randomized, double-blind research study will use functional magnetic resonance neuroimaging using state-of-the-art HCP acquisition protocols and analytic pipelines, to identify predictors and correlates of response to an accepted first-line pharmacological treatment for obsessive-compulsive disorder.

Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD

Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD

Condition
Obsessive-Compulsive Disorder
Intervention / Treatment

-

Contacts and Locations

New Haven

Yale OCD Research Clinic - CMHC/CNRU, 34 Park ST, New Haven, Connecticut, United States, 06519

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Inclusion criteria for all groups will include: (i) Adults, Men and women will be included, in a 1:1 ratio; and efforts will be made to recruit racial and ethnic subgroups. Groups will be further matched on age, handedness; and later, in analysis, on educational status and smoking history.
  • * Additional
  • * Exclusion criteria for all groups will include:
  • * Additional

Ages Eligible for Study

18 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Yale University,

Christopher Pittenger, MD, PhD, PRINCIPAL_INVESTIGATOR, Professor of Psychiatry; Director, Yale OCD Research Clinic

Study Record Dates

2025-12-31