Erector Spinae Plane Blockade in Pediatric Scoliosis Surgery Patients

Description

Providing effective analgesia after spinal fusion for idiopathic scoliosis remains a challenge with significant practice variation existing among high volume spine surgery centers. Even in the era of multimodal analgesia, opioids are the primary analgesics used for pain control after pediatric scoliosis surgery, but have multiple known adverse effects. The erector spinae plane block (ESPB) is a newly described fascial plane block performed by injecting local anesthetic between the erector spinae muscle and the transverse process. Additionally, there are case reports describing the ESPB as part of a multi-modal analgesic plan in adult degenerative spine surgery as well as adult spinal deformity surgery, demonstrating effective analgesia and no clinical motor blockade. Although it is known that the inflammatory reaction plays a crucial role in the mechanism of acute pain after major surgery, the effectiveness of the current regional approach on inflammatory response is not well studied.

Conditions

Scoliosis; Juvenile, Scoliosis; Adolescence

Study Overview

Study Details

Study overview

Providing effective analgesia after spinal fusion for idiopathic scoliosis remains a challenge with significant practice variation existing among high volume spine surgery centers. Even in the era of multimodal analgesia, opioids are the primary analgesics used for pain control after pediatric scoliosis surgery, but have multiple known adverse effects. The erector spinae plane block (ESPB) is a newly described fascial plane block performed by injecting local anesthetic between the erector spinae muscle and the transverse process. Additionally, there are case reports describing the ESPB as part of a multi-modal analgesic plan in adult degenerative spine surgery as well as adult spinal deformity surgery, demonstrating effective analgesia and no clinical motor blockade. Although it is known that the inflammatory reaction plays a crucial role in the mechanism of acute pain after major surgery, the effectiveness of the current regional approach on inflammatory response is not well studied.

Pediatric Scoliosis Surgery: Enhanced Recovery With Erector Spinae Plane Blockade Utilizing Surgically Placed Catheters

Erector Spinae Plane Blockade in Pediatric Scoliosis Surgery Patients

Condition
Scoliosis; Juvenile
Intervention / Treatment

-

Contacts and Locations

Palo Alto

Lucille Packard Children's Hospital, Palo Alto, California, United States, 94304

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

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Eligibility Criteria

  • * ASA I-III
  • * Diagnosed with Idiopathic scoliosis
  • * Undergoing single-stage posterior spinal instrumentation and fusion
  • * Thorascopic tethering procedure
  • * Two-stage procedure
  • * Abnormal developmental profile
  • * Congenital/neuromuscular scoliosis
  • * Requiring PICU admission
  • * Known allergy to lidocaine
  • * Known cardiac, renal or liver disease or dysfunction
  • * Pre-existing pain complaints, i.e. on regular analgesic medications
  • * Current psychiatric diagnosis, e.g. anxiety, depression, eating disorder, defined according to DSM criteria.
  • * Requiring non-standard post-op pain management
  • * Any history of seizures
  • * Unplanned staged procedure
  • * Weight \< 5th centile or \> 85th centile for age
  • * Porphyria

Ages Eligible for Study

to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Stanford University,

Study Record Dates

2024-10