RECRUITING

Duke APOL1 Research Biorepository

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The Duke ApoL1 Nephropathy Biorepository aims to address needs within non-diabetic kidney failure research by utilizing existing and, when necessary, developing new infrastructure to support the consent of patients and the collection of dedicated samples for ApoL1 Nephropathy biorepository. The mutations in ApoL1 gene that are strongly associated with kidney disease are only present in individuals of recent African ancestry (i.e., black people). Caucasians do not have these ApoL1 mutations nor the associated kidney disease. Therefore, majority of subjects recruited for this study will be self-identified African Americans, Afro-Caribbean and other black individual. Study subjects will include individuals with end stage kidney disease and those without any clinical evidence of kidney disease. Additionally, healthy black adults with no known history of kidney disease will be recruited as controls in this study because they are the only group that can fill this role.

Official Title

Duke APOL1 Research Biorepository

Quick Facts

Study Start:2019-12-13
Study Completion:2024-11-15
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04160507

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Majority of subjects recruited for this study will be self-identified African Americans, Afro-Caribbean and other black individuals. Study subjects will include individuals at various stages of kidney disease and those without any clinical evidence of kidney disease.
  2. * Healthy black adults, age 50 and older with no known history of kidney disease will be recruited as controls
  1. * Black adult cases with diabetic nephropathy
  2. * Healthy controls with kidney disease

Contacts and Locations

Study Contact

Opeyemi Olabisi, MD/PHD
CONTACT
919-660-6987
opeyemi.olabisi@duke.edu
Maurice W Smith, MA
CONTACT
9196131386
maurice.w.smith@duke.edu

Study Locations (Sites)

Duke University Medical Center
Durham, North Carolina, 27705
United States

Collaborators and Investigators

Sponsor: Duke University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-12-13
Study Completion Date2024-11-15

Study Record Updates

Study Start Date2019-12-13
Study Completion Date2024-11-15

Terms related to this study

Keywords Provided by Researchers

  • ESKD
  • APOL 1 gene
  • Kidney Disease

Additional Relevant MeSH Terms

  • End Stage Kidney Disease