Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms

Description

This study aims to look at the long term efficacy of using repetitive transcranial magnetic stimulation (rTMS) in relieving Gulf War Illness related headaches and pain.

Conditions

Gulf War Syndrome, Gulf War Illness, Headache, Muscle Pain, Joint Pain

Talk to us

Study Overview

On this page

Study Details

Study overview

This study aims to look at the long term efficacy of using repetitive transcranial magnetic stimulation (rTMS) in relieving Gulf War Illness related headaches and pain.

Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms

Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms

Condition
Gulf War Syndrome
Intervention / Treatment

-

Contacts and Locations

Palo Alto

VA Palo Alto, Palo Alto, California, United States, 94304

San Diego

VA San Diego Healthcare System, San Diego, California, United States, 92161

Decatur

VA Atlanta, Decatur, Georgia, United States, 30033

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Male or female under 65 years of age who served in the military for at least 30 consecutive days between August 1, 1990, and July 31, 1991 in the Persian Gulf War region
  • * Center for Disease Control (CDC) Criteria for Gulf War Illness (GWI)
  • * Kansas Criteria for GWI
  • * International Headache Society Criteria for Migraine Headache without aura Average Headache Exacerbation Intensity \>3 on 0-10 a Numerical Pain Rating scale (NPS)
  • * Average Overall Daily Muscle Pain Intensity \>3 on 0-10 a NPS
  • * Average Overall Daily Extremities Joint Pain Intensity \>3 on 0-10 a NPS
  • * Headache Exacerbation/attack 3 times per week with the average intensity \>3 on a 0-10 NPS, lasting \> 4 hours in the past three months
  • * Hamilton Rating Scale of Depression (HRSD) \<14 based on the sum of scores for the first 17 items
  • * Pregnancy
  • * History of pacemaker implant
  • * Any ferromagnetic (e.g. bullet fragment, shrapnel, device implant) in the brain or body that will prohibit the patients from having a brain MRI
  • * History of dementia, major psychiatric diseases, or life-threatening diseases
  • * Presence of any other chronic neuropathic pain states such as Complex Regional Pain Syndrome or Painful Peripheral Neuropathy
  • * History of seizure
  • * Pending litigation
  • * Low back pain with mechanical origins such as lumbar radiculopathy or radiculitis or lumbar facet arthropathy
  • * Lack of ability to understand the experimental protocol and to adequately communicate in English
  • * History of Traumatic Brain injury
  • * Chronic Tension or Cluster Headache
  • * Ongoing Cognitive Rehabilitation or Treatment of PTSD

Ages Eligible for Study

18 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Veterans Medical Research Foundation,

Albert Leung, M.D., PRINCIPAL_INVESTIGATOR, San Diego Veterans Healthcare System

Study Record Dates

2023-09-30