Use of Brain Wave Monitoring During Surgery to Reduce Postoperative Cognitive Dysfunction

Description

This research study is being done to determine if indices derived from monitoring brain wave activity while under general anesthesia will predict the likelihood of post-operative cognitive dysfunction in patients over 60 years old.

Conditions

Postoperative Cognitive Dysfunction

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Study Overview

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Study Details

Study overview

This research study is being done to determine if indices derived from monitoring brain wave activity while under general anesthesia will predict the likelihood of post-operative cognitive dysfunction in patients over 60 years old.

The Role of Brain Wave Monitoring in Reducing the Incidence of Postoperative Cognitive Dysfunction

Use of Brain Wave Monitoring During Surgery to Reduce Postoperative Cognitive Dysfunction

Condition
Postoperative Cognitive Dysfunction
Intervention / Treatment

-

Contacts and Locations

Lebanon

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States, 03756

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 60-80 years of age who present for elective, non-cardiac surgical procedure requiring general anesthesia and an anticipated two-day or longer inpatient hospital stay
  • * English as the native and primary language
  • * Presence of an informant who has had weekly contact with the participant for at least the last year
  • * Participant is capable of providing written informed consent.
  • * history of persistent and severe mental illness (e.g., schizophrenia, bipolar disorder)
  • * neurological disorder (e.g., Parkinson's disease, epilepsy, stroke)
  • * active substance use disorder as defined by the Diagnostic and Statistical Manual Diploma in Social Medicine(DSM-V)
  • * history of prior diagnosis of learning disability per the DSM-V
  • * estimated premorbid intellectual functioning below a scaled score of 70 based on the Test of Premorbid Functioning (TOPF)
  • * severe visual or hearing impairments that prevent the participant from undergoing the neurocognitive assessment.

Ages Eligible for Study

60 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Dartmouth-Hitchcock Medical Center,

M. Dustin Boone, MD, PRINCIPAL_INVESTIGATOR, Dartmouth-Hitchcock Medical Center

Study Record Dates

2025-01