COMPLETED

Use of Brain Wave Monitoring During Surgery to Reduce Postoperative Cognitive Dysfunction

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This research study is being done to determine if indices derived from monitoring brain wave activity while under general anesthesia will predict the likelihood of post-operative cognitive dysfunction in patients over 60 years old.

Official Title

The Role of Brain Wave Monitoring in Reducing the Incidence of Postoperative Cognitive Dysfunction

Quick Facts

Study Start:2020-01-24

Study Completion:2025-11-11

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:COMPLETED

Study ID

NCT04189861

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years to 80 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* 60-80 years of age who present for elective, non-cardiac surgical procedure requiring general anesthesia and an anticipated two-day or longer inpatient hospital stay * English as the native and primary language * Presence of an informant who has had weekly contact with the participant for at least the last year * Participant is capable of providing written informed consent.	* history of persistent and severe mental illness (e.g., schizophrenia, bipolar disorder) * neurological disorder (e.g., Parkinson's disease, epilepsy, stroke) * active substance use disorder as defined by the Diagnostic and Statistical Manual Diploma in Social Medicine(DSM-V) * history of prior diagnosis of learning disability per the DSM-V * estimated premorbid intellectual functioning below a scaled score of 70 based on the Test of Premorbid Functioning (TOPF) * severe visual or hearing impairments that prevent the participant from undergoing the neurocognitive assessment.

Inclusion Criteria

Exclusion Criteria

* 60-80 years of age who present for elective, non-cardiac surgical procedure requiring general anesthesia and an anticipated two-day or longer inpatient hospital stay
* English as the native and primary language
* Presence of an informant who has had weekly contact with the participant for at least the last year
* Participant is capable of providing written informed consent.

* history of persistent and severe mental illness (e.g., schizophrenia, bipolar disorder)
* neurological disorder (e.g., Parkinson's disease, epilepsy, stroke)
* active substance use disorder as defined by the Diagnostic and Statistical Manual Diploma in Social Medicine(DSM-V)
* history of prior diagnosis of learning disability per the DSM-V
* estimated premorbid intellectual functioning below a scaled score of 70 based on the Test of Premorbid Functioning (TOPF)
* severe visual or hearing impairments that prevent the participant from undergoing the neurocognitive assessment.

Contacts and Locations

Principal Investigator

M. Dustin Boone, MD

PRINCIPAL_INVESTIGATOR

Dartmouth-Hitchcock Medical Center

Study Locations (Sites)

Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, 03756

United States

Collaborators and Investigators

Sponsor: Dartmouth-Hitchcock Medical Center

M. Dustin Boone, MD, PRINCIPAL_INVESTIGATOR, Dartmouth-Hitchcock Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-01-24

Study Completion Date2025-11-11

Study Record Updates

Study Start Date2020-01-24

Study Completion Date2025-11-11

Terms related to this study

Additional Relevant MeSH Terms

Postoperative Cognitive Dysfunction