Complex Adult Deformity Surgery (CADS)

Description

Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.

Conditions

Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance

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Study Overview

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Study Details

Study overview

Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.

Multi-Center Prospective Evaluation of Complex Adult Spinal Deformity Surgery

Complex Adult Deformity Surgery (CADS)

Condition
Adult Spinal Deformity
Intervention / Treatment

-

Contacts and Locations

La Jolla

Shiley Center for Orthopaedic Research and Education at Scripps Clinic, La Jolla, California, United States, 92037

Sacramento

University of California, Davis, Department of Orthopedic Surgery, Sacramento, California, United States, 05616

San Francisco

UCSF, Department of Neurosurgery, San Francisco, California, United States, 94143

Denver

Denver International Spine Center, Rocky Mountain Hospital for Children and Presbyterian St. Luke's Medical Center, Denver, Colorado, United States, 80218

Kansas City

University of Kansas, Department of Orthopedic Surgery, Kansas City, Kansas, United States, 66160

Louisville

Norton Leatherman Spine Center, Louisville, Kentucky, United States, 40207

Shreveport

Spine Institute of Louisiana, Shreveport, Louisiana, United States, 71101

Baltimore

John Hopkins University, Department of Orthopedic Surgery, Baltimore, Maryland, United States, 21224

Saint Louis

Washington University, Department of Orthopedic Surgery, Saint Louis, Missouri, United States, 63310

New York

NYU, Department of Orthopedics, New York, New York, United States, 10016

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Diagnosis of adult congenital, degenerative, idiopathic or iatrogenic spinal deformity
  • 2. Full body EOS radiographic assessment (sagittal and coronal visualization from skull to foot)
  • 3. Complex patients are defined as and meeting any one of the subsequent criteria:
  • 1. Radiographic criteria:
  • * PI-LL ≥ 25 degrees
  • * TPA ≥ 30 degrees
  • * SVA\>15cm
  • * Thoracic scoliosis ≥ 70 degrees
  • * Thoracolumbar/lumbar scoliosis ≥ 50 degrees
  • * Global coronal malalignment \>7cm
  • 2. Procedural criteria:
  • * Posterior spinal fusion \> 12 levels
  • * 3 column osteotomy or ACR
  • 3. Geriatric criteria:
  • * Age \>65 years and minimum 7 levels of spinal instrumentation during surgery
  • 1. Age \<18 years of age
  • 2. Active spine tumor or infection
  • 3. Deformity due to acute trauma
  • 4. Neuromuscular conditions/diseases (Parkinson's, Multiple Sclerosis, Post-polio syndrome)
  • 5. Syndromic scoliosis
  • 6. Inflammatory arthritis/auto immune diseases (Rheumatoid arthritis, Lupus, Ankylosing Spondylitis)
  • 7. Prisoners
  • 8. Women who are pregnant
  • 9. Non English speaking patients

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

International Spine Study Group Foundation,

Shay Bess, MD, PRINCIPAL_INVESTIGATOR, Denver International Spine Center

Lawrence Lenke, MD, PRINCIPAL_INVESTIGATOR, Columbia University, Department of Orthopedic Surgery

Christopher Shaffrey, MD, PRINCIPAL_INVESTIGATOR, Duke University, Departments of Neurosurgery and Orthopaedic Surgery

Study Record Dates

2032-07-31