RECRUITING

Heart Failure Precision Medicine Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The study aims to test the hypothesis that multi-omics studies can identify Heart Failure profiles at risk of adverse outcomes and evaluate a telemonitoring intervention in the optimization of guideline-directed medical therapy.

Official Title

Heart Failure Precision Medicine Study

Quick Facts

Study Start:2019-10-16
Study Completion:2026-10-16
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT04196842

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:21 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Diagnosis of Heart failure
  2. * Objective evidence of cardiac abnormality of structure or function (abnormal ECHO) or elevated levels of B-type natriuretic peptide (\>100 pg/ml)
  3. * HF stage B-D and class I-IV
  1. * Patients unable to consent
  2. * Inability to comply with the protocol and follow-up requirements
  3. * Patients unable to use a smartphone
  4. * Patients assessed irregularly (less than two visits in one year)
  5. * History of HTx
  6. * Use of Mechanical circulatory support device (MCSD)
  7. * Comorbidities that, according to the PI, have the potential to interfere with the interpretation of the results

Contacts and Locations

Study Contact

Erick S Romero, MD
CONTACT
(916) 703-2071
esromero@ucdavis.edu

Principal Investigator

Martin Cadeiras, MD
PRINCIPAL_INVESTIGATOR
University of California, Davis

Study Locations (Sites)

UC Davis Medical Center
Sacramento, California, 95817
United States

Collaborators and Investigators

Sponsor: University of California, Davis

  • Martin Cadeiras, MD, PRINCIPAL_INVESTIGATOR, University of California, Davis

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-10-16
Study Completion Date2026-10-16

Study Record Updates

Study Start Date2019-10-16
Study Completion Date2026-10-16

Terms related to this study

Keywords Provided by Researchers

  • Heart Failure
  • Multi-omics
  • Phenomapping
  • Precision medicine
  • Telemonitoring

Additional Relevant MeSH Terms

  • Heart Failure