RECRUITING

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

Conditions

Metastatic Small Intestinal Adenocarcinoma Stage III Small Intestinal Adenocarcinoma AJCC v8 Stage IIIA Small Intestinal Adenocarcinoma AJCC v8 Stage IIIB Small Intestinal Adenocarcinoma AJCC v8 Stage IV Small Intestinal Adenocarcinoma AJCC v8

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This phase II trial studies how well ramucirumab and paclitaxel or the FOLFIRI regimen (leucovorin calcium, fluorouracil, and irinotecan hydrochloride) work in treating patients with small bowel cancers that have spread extensively to other anatomic sites (advanced) or are no longer responding to treatment (refractory). Ramucirumab is a monoclonal antibody that attaches to and inhibits a molecule called VEGFR-2. This may restrain new blood vessel formation therefore reducing nutrient supply to tumor which may interfere with tumor cell growth and expansion. Drugs used in chemotherapy, such as paclitaxel, leucovorin calcium, fluorouracil, and irinotecan hydrochloride work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving Ramucirumab plus paclitaxel or FOLFIRI, may be helpful in treating advanced or refractory small bowel cancers and may help patients live longer.

Official Title

Randomized Phase II Selection Study of Ramucirumab and Paclitaxel Versus FOLFIRI in Refractory Small Bowel Adenocarcinoma

Quick Facts

Study Start:2020-06-01

Study Completion:2025-06-16

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT04205968

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Patients must have histologically or cytologically confirmed small bowel adenocarcinoma. Ampullary adenocarcinomas are not eligible. Patients must have metastatic disease or locally advanced unresectable disease * Brain metastases are allowed if they have been adequately treated with radiotherapy or surgery and stable for at least 30 days prior to registration. Patients must be neurologically asymptomatic and without corticosteroid treatment for at least 7 days prior to registration * Patients must have measurable or non-measurable disease. All scans needed for assessment of measurable disease must be performed within 28 days prior to registration. Non-measurable disease must be assessed within 42 days prior to registration. All disease must be assessed and documented on the Baseline Tumor Assessment Form * Patients must have progressed on prior therapy with a fluoropyrimidine and/or oxaliplatin, given either for metastatic/locally advanced disease or as adjuvant therapy completed within the previous 12 months * Patients must have completed prior chemotherapy, immunotherapy, or radiation therapy at least 14 days prior to registration and all toxicity must be resolved to grade 1 (with the exception of grade 2 neuropathy) prior to registration. In Common Terminology Criteria for Adverse Events (CTCAE) version 5.0 grade 2 sensory neuropathy is defined as "moderate symptoms; limiting instrumental activities of daily living (ADLs)" * Patients must have a complete medical history and physical exam within 28 days prior to registration * Patients must have a Zubrod performance status of 0 or 1 * Absolute neutrophil count (ANC) \>= 1,500/mcL (must be obtained within 28 days prior to registration) * Platelets \>= 100,000/mcL (must be obtained within 28 days prior to registration) * A total bilirubin =\< 1.5 x institutional limit normal (IULN) (must be obtained within 28 days prior to registration) * Serum glutamic-oxaloacetic transaminase (SGOT) (aspartate aminotransferase \[AST\]) and serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase \[ALT\]) =\< 3.0 x IULN (or 5.0 x IULN if liver metastases are present) (must be obtained within 28 days prior to registration) * Serum creatinine =\< 1.5 x IULN OR calculated creatinine clearance \>= 40 mL/min (must have been obtained within 28 days prior to registration) * Patient must have urinary protein =\< 1+ on dipstick or routine urinalysis (UA) within 28 days prior to registration. If dipstick or routine analysis is \>= 2+, a 24 - hour urine collections for protein must demonstrate \< 1000 mg of protein in 24 hours * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial * Patients must not have known dihydropyrimidine dehydrogenase deficiency * Patients must be offered the opportunity to participate in specimen banking * Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines	* Patients must not have received prior treatment with irinotecan, taxane, or ramucirumab for small bowel adenocarcinoma * Patients must not have had major surgery within 28 days prior to registration, or minor surgery within 7 days prior to registration, and must not be planned for elective major surgery to be performed during protocol treatment * Patients must not be currently enrolled in or have discontinued within the last 28 days a clinical trial involving an investigational product or non-approved use of a drug, or concurrently enrolled in any other type of medical research judged not to be scientifically or medically compatible with this study. Patients participating in surveys or observational studies are eligible to participate in this study * Patients must not be receiving chronic antiplatelet therapy, including dipyridamole or clopidogrel, or similar agents * Patient must not have a known bleeding diathesis * Patient must not have uncontrolled or poorly-controlled hypertension (\> 160 mmHg systolic or \> 100 mg HG diastolic for \> 4 weeks) despite standard medical management * Patient tumors must not have known deficient mismatch repair (dMMR) or microsatellite instability high (MSI-H) * Patients must not be pregnant or nursing and must have had a negative pregnancy test within 4 weeks of starting treatment. Women/men of reproductive potential must have agreed to use an effective contraceptive method. A woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months. In addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation. However, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures * Patients must not have an active infection requiring systemic therapy * Patient must not have liver dysfunctions manifested by either (1) Child-Pugh B (or worse) or (2) cirrhosis (any degree) and a history of hepatic encephalopathy or clinically meaningful ascites resulting from cirrhosis. Clinically meaningful ascites is defined as ascites from cirrhosis requiring diuretics or paracentesis * Patients must not have a history of deep vein thrombosis (DVT), pulmonary embolism (PE), or any other significant thromboembolism (venous port or catheter thrombosis or superficial venous thrombosis are not considered "significant") during the 90 days prior to registration * Patients must not have experienced any arterial thrombotic event (including but not limited to myocardial infarction, unstable angina, stable angina markedly limiting ordinary physical activity, cerebrovascular accident, or transient ischemic attack) within 120 days prior to registration * Patients must not have a prior history of gastrointestinal (GI) perforation/fistula or other risk factors for perforation within 120 days prior to registration * Patients must not have experienced any grade 3-4 GI bleeding within 90 days prior to registration * Patient must not have experienced any serious or non-healing wound, ulcer, or bone fracture within 28 days prior to registration

Inclusion Criteria

Exclusion Criteria

* Patients must have histologically or cytologically confirmed small bowel adenocarcinoma. Ampullary adenocarcinomas are not eligible. Patients must have metastatic disease or locally advanced unresectable disease
* Brain metastases are allowed if they have been adequately treated with radiotherapy or surgery and stable for at least 30 days prior to registration. Patients must be neurologically asymptomatic and without corticosteroid treatment for at least 7 days prior to registration
* Patients must have measurable or non-measurable disease. All scans needed for assessment of measurable disease must be performed within 28 days prior to registration. Non-measurable disease must be assessed within 42 days prior to registration. All disease must be assessed and documented on the Baseline Tumor Assessment Form
* Patients must have progressed on prior therapy with a fluoropyrimidine and/or oxaliplatin, given either for metastatic/locally advanced disease or as adjuvant therapy completed within the previous 12 months
* Patients must have completed prior chemotherapy, immunotherapy, or radiation therapy at least 14 days prior to registration and all toxicity must be resolved to grade 1 (with the exception of grade 2 neuropathy) prior to registration. In Common Terminology Criteria for Adverse Events (CTCAE) version 5.0 grade 2 sensory neuropathy is defined as "moderate symptoms; limiting instrumental activities of daily living (ADLs)"
* Patients must have a complete medical history and physical exam within 28 days prior to registration
* Patients must have a Zubrod performance status of 0 or 1
* Absolute neutrophil count (ANC) \>= 1,500/mcL (must be obtained within 28 days prior to registration)
* Platelets \>= 100,000/mcL (must be obtained within 28 days prior to registration)
* A total bilirubin =\< 1.5 x institutional limit normal (IULN) (must be obtained within 28 days prior to registration)
* Serum glutamic-oxaloacetic transaminase (SGOT) (aspartate aminotransferase \[AST\]) and serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase \[ALT\]) =\< 3.0 x IULN (or 5.0 x IULN if liver metastases are present) (must be obtained within 28 days prior to registration)
* Serum creatinine =\< 1.5 x IULN OR calculated creatinine clearance \>= 40 mL/min (must have been obtained within 28 days prior to registration)
* Patient must have urinary protein =\< 1+ on dipstick or routine urinalysis (UA) within 28 days prior to registration. If dipstick or routine analysis is \>= 2+, a 24 - hour urine collections for protein must demonstrate \< 1000 mg of protein in 24 hours
* Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial
* Patients must not have known dihydropyrimidine dehydrogenase deficiency
* Patients must be offered the opportunity to participate in specimen banking
* Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines

* Patients must not have received prior treatment with irinotecan, taxane, or ramucirumab for small bowel adenocarcinoma
* Patients must not have had major surgery within 28 days prior to registration, or minor surgery within 7 days prior to registration, and must not be planned for elective major surgery to be performed during protocol treatment
* Patients must not be currently enrolled in or have discontinued within the last 28 days a clinical trial involving an investigational product or non-approved use of a drug, or concurrently enrolled in any other type of medical research judged not to be scientifically or medically compatible with this study. Patients participating in surveys or observational studies are eligible to participate in this study
* Patients must not be receiving chronic antiplatelet therapy, including dipyridamole or clopidogrel, or similar agents
* Patient must not have a known bleeding diathesis
* Patient must not have uncontrolled or poorly-controlled hypertension (\> 160 mmHg systolic or \> 100 mg HG diastolic for \> 4 weeks) despite standard medical management
* Patient tumors must not have known deficient mismatch repair (dMMR) or microsatellite instability high (MSI-H)
* Patients must not be pregnant or nursing and must have had a negative pregnancy test within 4 weeks of starting treatment. Women/men of reproductive potential must have agreed to use an effective contraceptive method. A woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months. In addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation. However, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures
* Patients must not have an active infection requiring systemic therapy
* Patient must not have liver dysfunctions manifested by either (1) Child-Pugh B (or worse) or (2) cirrhosis (any degree) and a history of hepatic encephalopathy or clinically meaningful ascites resulting from cirrhosis. Clinically meaningful ascites is defined as ascites from cirrhosis requiring diuretics or paracentesis
* Patients must not have a history of deep vein thrombosis (DVT), pulmonary embolism (PE), or any other significant thromboembolism (venous port or catheter thrombosis or superficial venous thrombosis are not considered "significant") during the 90 days prior to registration
* Patients must not have experienced any arterial thrombotic event (including but not limited to myocardial infarction, unstable angina, stable angina markedly limiting ordinary physical activity, cerebrovascular accident, or transient ischemic attack) within 120 days prior to registration
* Patients must not have a prior history of gastrointestinal (GI) perforation/fistula or other risk factors for perforation within 120 days prior to registration
* Patients must not have experienced any grade 3-4 GI bleeding within 90 days prior to registration
* Patient must not have experienced any serious or non-healing wound, ulcer, or bone fracture within 28 days prior to registration

Contacts and Locations

Study Contact

Christy Klepetko

CONTACT

210/614-8808

cklepetko@swog.org

Dana Sparks

CONTACT

210/614-8808

dsparks@swog.org

Principal Investigator

Michael J Overman

PRINCIPAL_INVESTIGATOR

SWOG Cancer Research Network

Study Locations (Sites)

Anchorage Associates in Radiation Medicine

Anchorage, Alaska, 98508

United States

Anchorage Radiation Therapy Center

Anchorage, Alaska, 99504

United States

Alaska Breast Care and Surgery LLC

Anchorage, Alaska, 99508

United States

Alaska Oncology and Hematology LLC

Anchorage, Alaska, 99508

United States

Alaska Women's Cancer Care

Anchorage, Alaska, 99508

United States

Anchorage Oncology Centre

Anchorage, Alaska, 99508

United States

Katmai Oncology Group

Anchorage, Alaska, 99508

United States

Providence Alaska Medical Center

Anchorage, Alaska, 99508

United States

Kingman Regional Medical Center

Kingman, Arizona, 86401

United States

Cancer Center at Saint Joseph's

Phoenix, Arizona, 85004

United States

Mercy Hospital Fort Smith

Fort Smith, Arkansas, 72903

United States

CHI Saint Vincent Cancer Center Hot Springs

Hot Springs, Arkansas, 71913

United States

Kaiser Permanente-Anaheim

Anaheim, California, 92806

United States

Mission Hope Medical Oncology - Arroyo Grande

Arroyo Grande, California, 93420

United States

PCR Oncology

Arroyo Grande, California, 93420

United States

Kaiser Permanente-Baldwin Park

Baldwin Park, California, 91706

United States

Kaiser Permanente-Bellflower

Bellflower, California, 90706

United States

Providence Saint Joseph Medical Center/Disney Family Cancer Center

Burbank, California, 91505

United States

Mercy Cancer Center �� Carmichael

Carmichael, California, 95608

United States

Mercy San Juan Medical Center

Carmichael, California, 95608

United States

Mercy Cancer Center - Elk Grove

Elk Grove, California, 95758

United States

Kaiser Permanente-Fontana

Fontana, California, 92335

United States

Kaiser Permanente - Harbor City

Harbor City, California, 90710

United States

Kaiser Permanente-Irvine

Irvine, California, 92618

United States

Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, 90027

United States

Kaiser Permanente West Los Angeles

Los Angeles, California, 90034

United States

Providence Queen of The Valley

Napa, California, 94558

United States

Kaiser Permanente-Ontario

Ontario, California, 91761

United States

Kaiser Permanente - Panorama City

Panorama City, California, 91402

United States

Kaiser Permanente-Riverside

Riverside, California, 92505

United States

Mercy Cancer Center - Rocklin

Rocklin, California, 95765

United States

Mercy Cancer Center - Sacramento

Sacramento, California, 95816

United States

Kaiser Permanente-San Diego Mission

San Diego, California, 92108

United States

Kaiser Permanente-San Diego Zion

San Diego, California, 92120

United States

Pacific Central Coast Health Center-San Luis Obispo

San Luis Obispo, California, 93401

United States

Kaiser Permanente-San Marcos

San Marcos, California, 92078

United States

Mission Hope Medical Oncology - Santa Maria

Santa Maria, California, 93444

United States

Providence Medical Foundation - Santa Rosa

Santa Rosa, California, 95403

United States

Providence Santa Rosa Memorial Hospital

Santa Rosa, California, 95405

United States

Kaiser Permanente-Woodland Hills

Woodland Hills, California, 91367

United States

Woodland Memorial Hospital

Woodland, California, 95695

United States

Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907

United States

Rocky Mountain Cancer Centers-Penrose

Colorado Springs, Colorado, 80907

United States

Saint Francis Cancer Center

Colorado Springs, Colorado, 80923

United States

Porter Adventist Hospital

Denver, Colorado, 80210

United States

Mercy Medical Center

Durango, Colorado, 81301

United States

Southwest Oncology PC

Durango, Colorado, 81301

United States

Saint Anthony Hospital

Lakewood, Colorado, 80228

United States

Littleton Adventist Hospital

Littleton, Colorado, 80122

United States

Longmont United Hospital

Longmont, Colorado, 80501

United States

Rocky Mountain Cancer Centers-Longmont

Longmont, Colorado, 80501

United States

Parker Adventist Hospital

Parker, Colorado, 80138

United States

Saint Mary Corwin Medical Center

Pueblo, Colorado, 81004

United States

Holy Cross Hospital

Fort Lauderdale, Florida, 33308

United States

Regional Cancer Center-Lee Memorial Health System

Fort Myers, Florida, 33905

United States

Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706

United States

Saint Luke's Cancer Institute - Boise

Boise, Idaho, 83712

United States

Saint Alphonsus Cancer Care Center-Caldwell

Caldwell, Idaho, 83605

United States

Kootenai Health - Coeur d'Alene

Coeur d'Alene, Idaho, 83814

United States

Walter Knox Memorial Hospital

Emmett, Idaho, 83617

United States

Saint Luke's Cancer Institute - Fruitland

Fruitland, Idaho, 83619

United States

Idaho Urologic Institute-Meridian

Meridian, Idaho, 83642

United States

Saint Luke's Cancer Institute - Meridian

Meridian, Idaho, 83642

United States

Saint Luke's Cancer Institute - Nampa

Nampa, Idaho, 83686

United States

Saint Alphonsus Cancer Care Center-Nampa

Nampa, Idaho, 83687

United States

Kootenai Clinic Cancer Services - Post Falls

Post Falls, Idaho, 83854

United States

Kootenai Cancer Clinic

Sandpoint, Idaho, 83864

United States

Saint Luke's Cancer Institute - Twin Falls

Twin Falls, Idaho, 83301

United States

Saint Anthony's Health

Alton, Illinois, 62002

United States

Rush - Copley Medical Center

Aurora, Illinois, 60504

United States

Illinois CancerCare-Bloomington

Bloomington, Illinois, 61704

United States

Illinois CancerCare-Canton

Canton, Illinois, 61520

United States

Memorial Hospital of Carbondale

Carbondale, Illinois, 62902

United States

SIH Cancer Institute

Carterville, Illinois, 62918

United States

Illinois CancerCare-Carthage

Carthage, Illinois, 62321

United States

Centralia Oncology Clinic

Centralia, Illinois, 62801

United States

Saint Mary's Hospital

Centralia, Illinois, 62801

United States

Northwestern University

Chicago, Illinois, 60611

United States

University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637

United States

Carle at The Riverfront

Danville, Illinois, 61832

United States

Cancer Care Specialists of Illinois - Decatur

Decatur, Illinois, 62526

United States

Decatur Memorial Hospital

Decatur, Illinois, 62526

United States

Illinois CancerCare-Dixon

Dixon, Illinois, 61021

United States

Carle Physician Group-Effingham

Effingham, Illinois, 62401

United States

Crossroads Cancer Center

Effingham, Illinois, 62401

United States

Illinois CancerCare-Eureka

Eureka, Illinois, 61530

United States

Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401

United States

Western Illinois Cancer Treatment Center

Galesburg, Illinois, 61401

United States

Illinois CancerCare-Kewanee Clinic

Kewanee, Illinois, 61443

United States

Northwestern Medicine Lake Forest Hospital

Lake Forest, Illinois, 60045

United States

Illinois CancerCare-Macomb

Macomb, Illinois, 61455

United States

Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938

United States

Good Samaritan Regional Health Center

Mount Vernon, Illinois, 62864

United States

UC Comprehensive Cancer Center at Silver Cross

New Lenox, Illinois, 60451

United States

Cancer Care Center of O'Fallon

O'Fallon, Illinois, 62269

United States

University of Chicago Medicine-Orland Park

Orland Park, Illinois, 60462

United States

Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350

United States

Illinois CancerCare-Pekin

Pekin, Illinois, 61554

United States

Illinois CancerCare-Peoria

Peoria, Illinois, 61615

United States

Methodist Medical Center of Illinois

Peoria, Illinois, 61636

United States

Illinois CancerCare-Peru

Peru, Illinois, 61354

United States

Valley Radiation Oncology

Peru, Illinois, 61354

United States

Illinois CancerCare-Princeton

Princeton, Illinois, 61356

United States

Southern Illinois University School of Medicine

Springfield, Illinois, 62702

United States

Springfield Clinic

Springfield, Illinois, 62702

United States

Memorial Medical Center

Springfield, Illinois, 62781

United States

Southwest Illinois Health Services LLP

Swansea, Illinois, 62226

United States

Carle Cancer Center

Urbana, Illinois, 61801

United States

The Carle Foundation Hospital

Urbana, Illinois, 61801

United States

Illinois CancerCare - Washington

Washington, Illinois, 61571

United States

Rush-Copley Healthcare Center

Yorkville, Illinois, 60560

United States

Reid Health

Richmond, Indiana, 47374

United States

Mary Greeley Medical Center

Ames, Iowa, 50010

United States

McFarland Clinic - Ames

Ames, Iowa, 50010

United States

University of Iowa Healthcare Cancer Services Quad Cities

Bettendorf, Iowa, 52722

United States

McFarland Clinic - Boone

Boone, Iowa, 50036

United States

Saint Anthony Regional Hospital

Carroll, Iowa, 51401

United States

Medical Oncology and Hematology Associates-West Des Moines

Clive, Iowa, 50325

United States

Mercy Cancer Center-West Lakes

Clive, Iowa, 50325

United States

Alegent Health Mercy Hospital

Council Bluffs, Iowa, 51503

United States

Greater Regional Medical Center

Creston, Iowa, 50801

United States

Iowa Methodist Medical Center

Des Moines, Iowa, 50309

United States

Medical Oncology and Hematology Associates-Des Moines

Des Moines, Iowa, 50309

United States

Broadlawns Medical Center

Des Moines, Iowa, 50314

United States

Mercy Medical Center - Des Moines

Des Moines, Iowa, 50314

United States

Mission Cancer and Blood - Laurel

Des Moines, Iowa, 50314

United States

Iowa Lutheran Hospital

Des Moines, Iowa, 50316

United States

McFarland Clinic - Trinity Cancer Center

Fort Dodge, Iowa, 50501

United States

Trinity Regional Medical Center

Fort Dodge, Iowa, 50501

United States

University of Iowa/Holden Comprehensive Cancer Center

Iowa City, Iowa, 52242

United States

McFarland Clinic - Jefferson

Jefferson, Iowa, 50129

United States

McFarland Clinic - Marshalltown

Marshalltown, Iowa, 50158

United States

Methodist West Hospital

West Des Moines, Iowa, 50266-7700

United States

Mercy Medical Center-West Lakes

West Des Moines, Iowa, 50266

United States

Central Care Cancer Center - Garden City

Garden City, Kansas, 67846

United States

Central Care Cancer Center - Great Bend

Great Bend, Kansas, 67530

United States

Flaget Memorial Hospital

Bardstown, Kentucky, 40004

United States

Commonwealth Cancer Center-Corbin

Corbin, Kentucky, 40701

United States

Saint Joseph Hospital

Lexington, Kentucky, 40504

United States

Saint Joseph Radiation Oncology Resource Center

Lexington, Kentucky, 40504

United States

Saint Joseph Hospital East

Lexington, Kentucky, 40509

United States

Saint Joseph London

London, Kentucky, 40741

United States

Jewish Hospital

Louisville, Kentucky, 40202

United States

Saints Mary and Elizabeth Hospital

Louisville, Kentucky, 40215

United States

UofL Health Medical Center Northeast

Louisville, Kentucky, 40245

United States

Saint Joseph Mount Sterling

Mount Sterling, Kentucky, 40353

United States

Jewish Hospital Medical Center South

Shepherdsville, Kentucky, 40165

United States

Lafayette Family Cancer Center-EMMC

Brewer, Maine, 04412

United States

Mercy Medical Center

Springfield, Massachusetts, 01104

United States

Hickman Cancer Center

Adrian, Michigan, 49221

United States

Saint Joseph Mercy Hospital

Ann Arbor, Michigan, 48106

United States

University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109

United States

Saint Joseph Mercy Brighton

Brighton, Michigan, 48114

United States

Trinity Health IHA Medical Group Hematology Oncology - Brighton

Brighton, Michigan, 48114

United States

University of Michigan - Brighton Center for Specialty Care

Brighton, Michigan, 48116

United States

Saint Joseph Mercy Canton

Canton, Michigan, 48188

United States

Trinity Health IHA Medical Group Hematology Oncology - Canton

Canton, Michigan, 48188

United States

Caro Cancer Center

Caro, Michigan, 48723

United States

Saint Joseph Mercy Chelsea

Chelsea, Michigan, 48118

United States

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

Chelsea, Michigan, 48118

United States

Hematology Oncology Consultants-Clarkston

Clarkston, Michigan, 48346

United States

Newland Medical Associates-Clarkston

Clarkston, Michigan, 48346

United States

Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201

United States

Ascension Saint John Hospital

Detroit, Michigan, 48236

United States

Great Lakes Cancer Management Specialists-Doctors Park

East China Township, Michigan, 48054

United States

Weisberg Cancer Treatment Center

Farmington Hills, Michigan, 48334

United States

Genesee Cancer and Blood Disease Treatment Center

Flint, Michigan, 48503

United States

Genesee Hematology Oncology PC

Flint, Michigan, 48503

United States

Genesys Hurley Cancer Institute

Flint, Michigan, 48503

United States

Hurley Medical Center

Flint, Michigan, 48503

United States

Academic Hematology Oncology Specialists

Grosse Pointe Woods, Michigan, 48236

United States

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center

Grosse Pointe Woods, Michigan, 48236

United States

Michigan Breast Specialists-Grosse Pointe Woods

Grosse Pointe Woods, Michigan, 48236

United States

Sparrow Hospital

Lansing, Michigan, 48912

United States

Hope Cancer Clinic

Livonia, Michigan, 48154

United States

Trinity Health Saint Mary Mercy Livonia Hospital

Livonia, Michigan, 48154

United States

Great Lakes Cancer Management Specialists-Macomb Medical Campus

Macomb, Michigan, 48044

United States

Michigan Breast Specialists-Macomb Township

Macomb, Michigan, 48044

United States

Saint Mary's Oncology/Hematology Associates of Marlette

Marlette, Michigan, 48453

United States

Toledo Clinic Cancer Centers-Monroe

Monroe, Michigan, 48162

United States

Ascension Providence Hospitals - Novi

Novi, Michigan, 48374

United States

21st Century Oncology-Pontiac

Pontiac, Michigan, 48341

United States

Hope Cancer Center

Pontiac, Michigan, 48341

United States

Newland Medical Associates-Pontiac

Pontiac, Michigan, 48341

United States

Saint Joseph Mercy Oakland

Pontiac, Michigan, 48341

United States

Great Lakes Cancer Management Specialists-Rochester Hills

Rochester Hills, Michigan, 48309

United States

Ascension Saint Mary's Hospital

Saginaw, Michigan, 48601

United States

Oncology Hematology Associates of Saginaw Valley PC

Saginaw, Michigan, 48604

United States

Ascension Providence Hospitals - Southfield

Southfield, Michigan, 48075

United States

Bhadresh Nayak MD PC-Sterling Heights

Sterling Heights, Michigan, 48312

United States

Ascension Saint Joseph Hospital

Tawas City, Michigan, 48764

United States

Advanced Breast Care Center PLLC

Warren, Michigan, 48088

United States

Great Lakes Cancer Management Specialists-Macomb Professional Building

Warren, Michigan, 48093

United States

Macomb Hematology Oncology PC

Warren, Michigan, 48093

United States

Michigan Breast Specialists-Warren

Warren, Michigan, 48093

United States

Saint John Macomb-Oakland Hospital

Warren, Michigan, 48093

United States

Saint Mary's Oncology/Hematology Associates of West Branch

West Branch, Michigan, 48661

United States

Huron Gastroenterology PC

Ypsilanti, Michigan, 48106

United States

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

Ypsilanti, Michigan, 48197

United States

Riverwood Healthcare Center

Aitkin, Minnesota, 56431

United States

Essentia Health - Baxter Clinic

Baxter, Minnesota, 56425

United States

Essentia Health Saint Joseph's Medical Center

Brainerd, Minnesota, 56401

United States

Fairview Ridges Hospital

Burnsville, Minnesota, 55337

United States

Minnesota Oncology - Burnsville

Burnsville, Minnesota, 55337

United States

Cambridge Medical Center

Cambridge, Minnesota, 55008

United States

Mercy Hospital

Coon Rapids, Minnesota, 55433

United States

Essentia Health - Deer River Clinic

Deer River, Minnesota, 56636

United States

Essentia Health Saint Mary's - Detroit Lakes Clinic

Detroit Lakes, Minnesota, 56501

United States

Essentia Health Cancer Center

Duluth, Minnesota, 55805

United States

Essentia Health Saint Mary's Medical Center

Duluth, Minnesota, 55805

United States

Miller-Dwan Hospital

Duluth, Minnesota, 55805

United States

Fairview Southdale Hospital

Edina, Minnesota, 55435

United States

Essentia Health - Ely Clinic

Ely, Minnesota, 55731

United States

Lake Region Healthcare Corporation-Cancer Care

Fergus Falls, Minnesota, 56537

United States

Essentia Health - Fosston

Fosston, Minnesota, 56542

United States

Unity Hospital

Fridley, Minnesota, 55432

United States

Essentia Health Hibbing Clinic

Hibbing, Minnesota, 55746

United States

Essentia Health - International Falls Clinic

International Falls, Minnesota, 56649

United States

Fairview Clinics and Surgery Center Maple Grove

Maple Grove, Minnesota, 55369

United States

Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109

United States

Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109

United States

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407

United States

Hennepin County Medical Center

Minneapolis, Minnesota, 55415

United States

Health Partners Inc

Minneapolis, Minnesota, 55454

United States

Monticello Cancer Center

Monticello, Minnesota, 55362

United States

Essentia Health - Moose Lake Clinic

Moose Lake, Minnesota, 55767

United States

New Ulm Medical Center

New Ulm, Minnesota, 56073

United States

Essentia Health - Park Rapids

Park Rapids, Minnesota, 56470

United States

Fairview Northland Medical Center

Princeton, Minnesota, 55371

United States

North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422

United States

Mayo Clinic in Rochester

Rochester, Minnesota, 55905

United States

Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416

United States

Regions Hospital

Saint Paul, Minnesota, 55101

United States

United Hospital

Saint Paul, Minnesota, 55102

United States

Essentia Health Sandstone

Sandstone, Minnesota, 55072

United States

Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379

United States

Lakeview Hospital

Stillwater, Minnesota, 55082

United States

Essentia Health Virginia Clinic

Virginia, Minnesota, 55792

United States

Ridgeview Medical Center

Waconia, Minnesota, 55387

United States

Rice Memorial Hospital

Willmar, Minnesota, 56201

United States

Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125

United States

Fairview Lakes Medical Center

Wyoming, Minnesota, 55092

United States

Baptist Cancer Center-Grenada

Grenada, Mississippi, 38901

United States

Baptist Memorial Hospital and Cancer Center-Union County

New Albany, Mississippi, 38652

United States

Baptist Memorial Hospital and Cancer Center-Oxford

Oxford, Mississippi, 38655

United States

Baptist Memorial Hospital and Cancer Center-Desoto

Southhaven, Mississippi, 38671

United States

Saint Louis Cancer and Breast Institute-Ballwin

Ballwin, Missouri, 63011

United States

Central Care Cancer Center - Bolivar

Bolivar, Missouri, 65613

United States

Cox Cancer Center Branson

Branson, Missouri, 65616

United States

Saint Francis Medical Center

Cape Girardeau, Missouri, 63703

United States

Southeast Cancer Center

Cape Girardeau, Missouri, 63703

United States

Siteman Cancer Center at West County Hospital

Creve Coeur, Missouri, 63141

United States

Parkland Health Center - Farmington

Farmington, Missouri, 63640

United States

Capital Region Southwest Campus

Jefferson City, Missouri, 65109

United States

Freeman Health System

Joplin, Missouri, 64804

United States

Mercy Hospital Joplin

Joplin, Missouri, 64804

United States

Delbert Day Cancer Institute at PCRMC

Rolla, Missouri, 65401

United States

Mercy Clinic-Rolla-Cancer and Hematology

Rolla, Missouri, 65401

United States

Heartland Regional Medical Center

Saint Joseph, Missouri, 64506

United States

Saint Louis Cancer and Breast Institute-South City

Saint Louis, Missouri, 63109

United States

Washington University School of Medicine

Saint Louis, Missouri, 63110

United States

Mercy Hospital South

Saint Louis, Missouri, 63128

United States

Siteman Cancer Center-South County

Saint Louis, Missouri, 63129

United States

Missouri Baptist Medical Center

Saint Louis, Missouri, 63131

United States

Siteman Cancer Center at Christian Hospital

Saint Louis, Missouri, 63136

United States

Mercy Hospital Saint Louis

Saint Louis, Missouri, 63141

United States

Siteman Cancer Center at Saint Peters Hospital

Saint Peters, Missouri, 63376

United States

Sainte Genevieve County Memorial Hospital

Sainte Genevieve, Missouri, 63670

United States

Mercy Hospital Springfield

Springfield, Missouri, 65804

United States

CoxHealth South Hospital

Springfield, Missouri, 65807

United States

Missouri Baptist Sullivan Hospital

Sullivan, Missouri, 63080

United States

Missouri Baptist Outpatient Center-Sunset Hills

Sunset Hills, Missouri, 63127

United States

Mercy Hospital Washington

Washington, Missouri, 63090

United States

Community Hospital of Anaconda

Anaconda, Montana, 59711

United States

Billings Clinic Cancer Center

Billings, Montana, 59101

United States

Bozeman Deaconess Hospital

Bozeman, Montana, 59715

United States

Benefis Healthcare- Sletten Cancer Institute

Great Falls, Montana, 59405

United States

Great Falls Clinic

Great Falls, Montana, 59405

United States

Kalispell Regional Medical Center

Kalispell, Montana, 59901

United States

Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802

United States

Community Medical Hospital

Missoula, Montana, 59804

United States

CHI Health Saint Francis

Grand Island, Nebraska, 68803

United States

CHI Health Good Samaritan

Kearney, Nebraska, 68847

United States

Saint Elizabeth Regional Medical Center

Lincoln, Nebraska, 68510

United States

Alegent Health Immanuel Medical Center

Omaha, Nebraska, 68122

United States

Alegent Health Bergan Mercy Medical Center

Omaha, Nebraska, 68124

United States

Alegent Health Lakeside Hospital

Omaha, Nebraska, 68130

United States

Creighton University Medical Center

Omaha, Nebraska, 68131

United States

Midlands Community Hospital

Papillion, Nebraska, 68046

United States

Carson Tahoe Regional Medical Center

Carson City, Nevada, 89703

United States

Cancer and Blood Specialists-Henderson

Henderson, Nevada, 89052

United States

Comprehensive Cancer Centers of Nevada - Henderson

Henderson, Nevada, 89052

United States

Comprehensive Cancer Centers of Nevada-Horizon Ridge

Henderson, Nevada, 89052

United States

Las Vegas Cancer Center-Henderson

Henderson, Nevada, 89052

United States

OptumCare Cancer Care at Seven Hills

Henderson, Nevada, 89052

United States

Comprehensive Cancer Centers of Nevada-Southeast Henderson

Henderson, Nevada, 89074

United States

GenesisCare USA - Henderson

Henderson, Nevada, 89074

United States

Las Vegas Urology - Green Valley

Henderson, Nevada, 89074

United States

Las Vegas Urology - Pebble

Henderson, Nevada, 89074

United States

Urology Specialists of Nevada - Green Valley

Henderson, Nevada, 89074

United States

Las Vegas Urology - Pecos

Las Vegas, Nevada, 89074

United States

Desert West Surgery

Las Vegas, Nevada, 89102

United States

OptumCare Cancer Care at Charleston

Las Vegas, Nevada, 89102

United States

University Medical Center of Southern Nevada

Las Vegas, Nevada, 89102

United States

Hope Cancer Care of Nevada

Las Vegas, Nevada, 89103

United States

Radiation Oncology Centers of Nevada Central

Las Vegas, Nevada, 89106

United States

Urology Specialists of Nevada - Central

Las Vegas, Nevada, 89106

United States

GenesisCare USA - Las Vegas

Las Vegas, Nevada, 89109

United States

Sunrise Hospital and Medical Center

Las Vegas, Nevada, 89109

United States

Las Vegas Prostate Cancer Center

Las Vegas, Nevada, 89113

United States

Las Vegas Urology - Sunset

Las Vegas, Nevada, 89113

United States

Urology Specialists of Nevada - Southwest

Las Vegas, Nevada, 89113

United States

Radiation Oncology Centers of Nevada Southeast

Las Vegas, Nevada, 89119

United States

Ann M Wierman MD LTD

Las Vegas, Nevada, 89128

United States

Comprehensive Cancer Centers of Nevada - Northwest

Las Vegas, Nevada, 89128

United States

GenesisCare USA - Vegas Tenaya

Las Vegas, Nevada, 89128

United States

Las Vegas Urology - Cathedral Rock

Las Vegas, Nevada, 89128

United States

Las Vegas Urology - Smoke Ranch

Las Vegas, Nevada, 89128

United States

OptumCare Cancer Care at MountainView

Las Vegas, Nevada, 89128

United States

Urology Specialists of Nevada - Northwest

Las Vegas, Nevada, 89128

United States

Alliance for Childhood Diseases/Cure 4 the Kids Foundation

Las Vegas, Nevada, 89135

United States

Comprehensive Cancer Centers of Nevada - Town Center

Las Vegas, Nevada, 89144

United States

Comprehensive Cancer Centers of Nevada-Summerlin

Las Vegas, Nevada, 89144

United States

Summerlin Hospital Medical Center

Las Vegas, Nevada, 89144

United States

Las Vegas Cancer Center-Medical Center

Las Vegas, Nevada, 89148-2405

United States

Comprehensive Cancer Centers of Nevada

Las Vegas, Nevada, 89148

United States

GenesisCare USA - Fort Apache

Las Vegas, Nevada, 89148

United States

OptumCare Cancer Care at Fort Apache

Las Vegas, Nevada, 89148

United States

Comprehensive Cancer Centers of Nevada - Central Valley

Las Vegas, Nevada, 89169

United States

University Cancer Center

Las Vegas, Nevada, 89169

United States

Hope Cancer Care of Nevada-Pahrump

Pahrump, Nevada, 89048

United States

Renown Regional Medical Center

Reno, Nevada, 89502

United States

Saint Mary's Regional Medical Center

Reno, Nevada, 89503

United States

Radiation Oncology Associates

Reno, Nevada, 89509

United States

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

Lebanon, New Hampshire, 03756

United States

Roswell Park Cancer Institute

Buffalo, New York, 14263

United States

University of Rochester

Rochester, New York, 14642

United States

Atrium Health Stanly/LCI-Albemarle

Albemarle, North Carolina, 28002

United States

Carolinas Medical Center/Levine Cancer Institute

Charlotte, North Carolina, 28203

United States

Atrium Health Pineville/LCI-Pineville

Charlotte, North Carolina, 28210

United States

Levine Cancer Institute-SouthPark

Charlotte, North Carolina, 28211

United States

Atrium Health University City/LCI-University

Charlotte, North Carolina, 28262

United States

Atrium Health Cabarrus/LCI-Concord

Concord, North Carolina, 28025

United States

Atrium Health Union/LCI-Union

Monroe, North Carolina, 28112

United States

Essentia Health Cancer Center-South University Clinic

Fargo, North Dakota, 58103

United States

Essentia Health - Jamestown Clinic

Jamestown, North Dakota, 58401

United States

Indu and Raj Soin Medical Center

Beavercreek, Ohio, 45431

United States

Saint Elizabeth Boardman Hospital

Boardman, Ohio, 44512

United States

Dayton Physicians LLC-Miami Valley South

Centerville, Ohio, 45459

United States

Miami Valley Hospital South

Centerville, Ohio, 45459

United States

Good Samaritan Hospital - Cincinnati

Cincinnati, Ohio, 45220

United States

Oncology Hematology Care Inc-Kenwood

Cincinnati, Ohio, 45236

United States

Bethesda North Hospital

Cincinnati, Ohio, 45242

United States

TriHealth Cancer Institute-Westside

Cincinnati, Ohio, 45247

United States

TriHealth Cancer Institute-Anderson

Cincinnati, Ohio, 45255

United States

Miami Valley Hospital

Dayton, Ohio, 45409

United States

Dayton Physician LLC-Miami Valley Hospital North

Dayton, Ohio, 45415

United States

Miami Valley Hospital North

Dayton, Ohio, 45415

United States

Armes Family Cancer Center

Findlay, Ohio, 45840

United States

Blanchard Valley Hospital

Findlay, Ohio, 45840

United States

Orion Cancer Care

Findlay, Ohio, 45840

United States

Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066

United States

Dayton Physicians LLC-Atrium

Franklin, Ohio, 45005

United States

Dayton Physicians LLC-Wayne

Greenville, Ohio, 45331

United States

Wayne Hospital

Greenville, Ohio, 45331

United States

Greater Dayton Cancer Center

Kettering, Ohio, 45409

United States

First Dayton Cancer Care

Kettering, Ohio, 45420

United States

Kettering Medical Center

Kettering, Ohio, 45429

United States

Toledo Clinic Cancer Centers-Maumee

Maumee, Ohio, 43537

United States

Mercy Health Perrysburg Cancer Center

Perrysburg, Ohio, 43551

United States

Springfield Regional Cancer Center

Springfield, Ohio, 45504

United States

Springfield Regional Medical Center

Springfield, Ohio, 45505

United States

Mercy Health - Saint Anne Hospital

Toledo, Ohio, 43623

United States

Toledo Clinic Cancer Centers-Toledo

Toledo, Ohio, 43623

United States

Dayton Physicians LLC - Troy

Troy, Ohio, 45373

United States

Upper Valley Medical Center

Troy, Ohio, 45373

United States

Saint Joseph Warren Hospital

Warren, Ohio, 44484

United States

Saint Elizabeth Youngstown Hospital

Youngstown, Ohio, 44501

United States

Cancer Centers of Southwest Oklahoma Research

Lawton, Oklahoma, 73505

United States

University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104

United States

Mercy Hospital Oklahoma City

Oklahoma City, Oklahoma, 73120

United States

Saint Alphonsus Medical Center-Baker City

Baker City, Oregon, 97814

United States

Saint Charles Health System

Bend, Oregon, 97701

United States

Clackamas Radiation Oncology Center

Clackamas, Oregon, 97015

United States

Providence Cancer Institute Clackamas Clinic

Clackamas, Oregon, 97015

United States

Bay Area Hospital

Coos Bay, Oregon, 97420

United States

Providence Newberg Medical Center

Newberg, Oregon, 97132

United States

Saint Alphonsus Medical Center-Ontario

Ontario, Oregon, 97914

United States

Providence Willamette Falls Medical Center

Oregon City, Oregon, 97045

United States

Providence Portland Medical Center

Portland, Oregon, 97213

United States

Providence Saint Vincent Medical Center

Portland, Oregon, 97225

United States

Saint Charles Health System-Redmond

Redmond, Oregon, 97756

United States

Lehigh Valley Hospital-Cedar Crest

Allentown, Pennsylvania, 18103

United States

Lehigh Valley Hospital - Muhlenberg

Bethlehem, Pennsylvania, 18017

United States

Pocono Medical Center

East Stroudsburg, Pennsylvania, 18301

United States

Lehigh Valley Hospital-Hazleton

Hazleton, Pennsylvania, 18201

United States

Prisma Health Cancer Institute - Spartanburg

Boiling Springs, South Carolina, 29316

United States

Prisma Health Cancer Institute - Easley

Easley, South Carolina, 29640

United States

Prisma Health Cancer Institute - Butternut

Greenville, South Carolina, 29605

United States

Prisma Health Cancer Institute - Faris

Greenville, South Carolina, 29605

United States

Prisma Health Greenville Memorial Hospital

Greenville, South Carolina, 29605

United States

Prisma Health Cancer Institute - Eastside

Greenville, South Carolina, 29615

United States

Prisma Health Cancer Institute - Greer

Greer, South Carolina, 29650

United States

Prisma Health Cancer Institute - Seneca

Seneca, South Carolina, 29672

United States

Baptist Memorial Hospital and Cancer Center-Collierville

Collierville, Tennessee, 38017

United States

Baptist Memorial Hospital and Cancer Center-Memphis

Memphis, Tennessee, 38120

United States

Saint Joseph Regional Cancer Center

Bryan, Texas, 77802

United States

Parkland Memorial Hospital

Dallas, Texas, 75235

United States

UT Southwestern/Simmons Cancer Center-Dallas

Dallas, Texas, 75390

United States

M D Anderson Cancer Center

Houston, Texas, 77030

United States

Norris Cotton Cancer Center-North

Saint Johnsbury, Vermont, 05819

United States

Providence Regional Cancer System-Aberdeen

Aberdeen, Washington, 98520

United States

Overlake Medical Center

Bellevue, Washington, 98004

United States

PeaceHealth Saint Joseph Medical Center

Bellingham, Washington, 98225

United States

Harrison HealthPartners Hematology and Oncology-Bremerton

Bremerton, Washington, 98310

United States

Harrison Medical Center

Bremerton, Washington, 98310

United States

Highline Medical Center-Main Campus

Burien, Washington, 98166

United States

Providence Regional Cancer System-Centralia

Centralia, Washington, 98531

United States

Swedish Cancer Institute-Edmonds

Edmonds, Washington, 98026

United States

Saint Elizabeth Hospital

Enumclaw, Washington, 98022

United States

Providence Regional Cancer Partnership

Everett, Washington, 98201

United States

Saint Francis Hospital

Federal Way, Washington, 98003

United States

Swedish Cancer Institute-Issaquah

Issaquah, Washington, 98029

United States

Kadlec Clinic Hematology and Oncology

Kennewick, Washington, 99336

United States

Providence Regional Cancer System-Lacey

Lacey, Washington, 98503

United States

Saint Clare Hospital

Lakewood, Washington, 98499

United States

PeaceHealth Saint John Medical Center

Longview, Washington, 98632

United States

Harrison HealthPartners Hematology and Oncology-Poulsbo

Poulsbo, Washington, 98370

United States

Valley Medical Center

Renton, Washington, 98055

United States

Pacific Gynecology Specialists

Seattle, Washington, 98104

United States

Swedish Medical Center-Ballard Campus

Seattle, Washington, 98107

United States

Swedish Medical Center-Cherry Hill

Seattle, Washington, 98122-5711

United States

Swedish Medical Center-First Hill

Seattle, Washington, 98122

United States

PeaceHealth United General Medical Center

Sedro-Woolley, Washington, 98284

United States

Providence Regional Cancer System-Shelton

Shelton, Washington, 98584

United States

Franciscan Research Center-Northwest Medical Plaza

Tacoma, Washington, 98405

United States

Northwest Medical Specialties PLLC

Tacoma, Washington, 98405

United States

PeaceHealth Southwest Medical Center

Vancouver, Washington, 98664

United States

Providence Saint Mary Regional Cancer Center

Walla Walla, Washington, 99362

United States

North Star Lodge Cancer Center at Yakima Valley Memorial Hospital

Yakima, Washington, 98902

United States

Providence Regional Cancer System-Yelm

Yelm, Washington, 98597

United States

Duluth Clinic Ashland

Ashland, Wisconsin, 54806

United States

Northwest Wisconsin Cancer Center

Ashland, Wisconsin, 54806

United States

Marshfield Clinic-Chippewa Center

Chippewa Falls, Wisconsin, 54729

United States

Marshfield Medical Center-EC Cancer Center

Eau Claire, Wisconsin, 54701

United States

Essentia Health-Hayward Clinic

Hayward, Wisconsin, 54843

United States

Marshfield Clinic - Ladysmith Center

Ladysmith, Wisconsin, 54848

United States

Marshfield Medical Center-Marshfield

Marshfield, Wisconsin, 54449

United States

Marshfield Clinic-Minocqua Center

Minocqua, Wisconsin, 54548

United States

ProHealth D N Greenwald Center

Mukwonago, Wisconsin, 53149

United States

Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017

United States

ProHealth Oconomowoc Memorial Hospital

Oconomowoc, Wisconsin, 53066

United States

Marshfield Medical Center-Rice Lake

Rice Lake, Wisconsin, 54868

United States

Essentia Health-Spooner Clinic

Spooner, Wisconsin, 54801

United States

Marshfield Medical Center-River Region at Stevens Point

Stevens Point, Wisconsin, 54482

United States

Essentia Health Saint Mary's Hospital - Superior

Superior, Wisconsin, 54880

United States

ProHealth Waukesha Memorial Hospital

Waukesha, Wisconsin, 53188

United States

UW Cancer Center at ProHealth Care

Waukesha, Wisconsin, 53188

United States

Marshfield Clinic-Wausau Center

Wausau, Wisconsin, 54401

United States

Marshfield Medical Center - Weston

Weston, Wisconsin, 54476

United States

Marshfield Clinic - Wisconsin Rapids Center

Wisconsin Rapids, Wisconsin, 54494

United States

Billings Clinic-Cody

Cody, Wyoming, 82414

United States

Welch Cancer Center

Sheridan, Wyoming, 82801

United States

Collaborators and Investigators

Sponsor: SWOG Cancer Research Network

Michael J Overman, PRINCIPAL_INVESTIGATOR, SWOG Cancer Research Network

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-06-01

Study Completion Date2025-06-16

Study Record Updates

Study Start Date2020-06-01

Study Completion Date2025-06-16

Terms related to this study

Additional Relevant MeSH Terms

Metastatic Small Intestinal Adenocarcinoma
Stage III Small Intestinal Adenocarcinoma AJCC v8
Stage IIIA Small Intestinal Adenocarcinoma AJCC v8
Stage IIIB Small Intestinal Adenocarcinoma AJCC v8
Stage IV Small Intestinal Adenocarcinoma AJCC v8