Duke Spine Outcome Study (DSOS)

Description

The primary goal of this registry is to increase the knowledge about spine tumors and other spine disorders to guide appropriate management strategies for the future. This registry will include the review of medical records, data collection for health related quality of life questionnaires, and collected tissues and samples. The study will require obtaining spinal lesions (tumor, etc.), blood, and bone marrow samples (from non-lesional bone) from selected patients, which will be collected during your surgery.

Conditions

Spinal Tumor, Spinal Disorder

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Study Overview

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Study Details

Study overview

The primary goal of this registry is to increase the knowledge about spine tumors and other spine disorders to guide appropriate management strategies for the future. This registry will include the review of medical records, data collection for health related quality of life questionnaires, and collected tissues and samples. The study will require obtaining spinal lesions (tumor, etc.), blood, and bone marrow samples (from non-lesional bone) from selected patients, which will be collected during your surgery.

Duke Spine Outcome Study (DSOS)

Duke Spine Outcome Study (DSOS)

Condition
Spinal Tumor
Intervention / Treatment

-

Contacts and Locations

Durham

Duke University Medical Center, Durham, North Carolina, United States, 27710

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age between 18 and 85 years.
  • * Able to read and write local language at an elementary level.
  • * Diagnosis of primary or metastatic tumor of the spine ); or
  • * Infection of the spine; or
  • * Instability of the spine; or
  • * Injury of the spine.
  • * Accessibility for treatment and follow up.
  • * Patient consent obtained according to Duke institutional policy.
  • * Age between 18 and 85 years.
  • * Spine surgery to be performed at Duke University Medical Center (DUMC) under the auspices of the neurosurgery program.
  • * No concurrent cancer diagnosis.
  • * Accessibility for treatment and follow up.
  • * Patient consent obtained according to Duke institutional policy.
  • * History of substance abuse (recreational drugs, alcohol) within 12 months prior to screening
  • * Is a prisoner.
  • * A disease or condition that would, in opinion of the investigator, preclude accurate evaluation
  • * Pregnant or breast feeding during the study period (women of child-bearing potential will require a negative serum pregnancy test within 30 days of enrollment).
  • * Active infection, or fever of unknown origin.
  • * Inflammatory bowel disease.
  • * Systemic lupus erythematosus.
  • * Rheumatoid arthritis, or other autoimmune disease.
  • * History of or active hematologic or bone marrow diseases, including but not limited to diagnosed lymphomas, leukemias, sickle cell or other anemias not associated with their current condition.
  • * Polycythemia vera.
  • * Known or suspected immunodeficiency or Human Immunodeficiency Virus (HIV).
  • * Hematocrit \< 24% pre-operatively.

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Duke University,

Courtney R. Goodwin, M.D., PhD, PRINCIPAL_INVESTIGATOR, Duke University

Study Record Dates

2026-12-01