Ketamine for Post-operative Analgesia in Hemorrhoidectomy

Description

This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids. The participants will be blinded to which treatment arm they are assigned, because participants will be under anesthesia when the ketamine is administered. The investigators will know whether the participant receives ketamine or not.

Conditions

Hemorrhoids

Study Overview

Study Details

Study overview

This is a prospective, randomized study of ketamine versus no ketamine in approximately 100 patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids. The participants will be blinded to which treatment arm they are assigned, because participants will be under anesthesia when the ketamine is administered. The investigators will know whether the participant receives ketamine or not.

Intra-operative Use of Ketamine for Post-Operative Analgesia in Patients Undergoing Hemorrhoidectomy: A Prospective, Randomized Controlled Trial.

Ketamine for Post-operative Analgesia in Hemorrhoidectomy

Condition
Hemorrhoids
Intervention / Treatment

-

Contacts and Locations

Oklahoma City

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States, 73104

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Adults aged 18-100
  • * Undergoing a hemorrhoidectomy for Grade III or IV hemorrhoids.
  • * Inability to undergo general anesthesia
  • * Contraindications to hemorrhoidectomy
  • * History of schizophrenia or other hallucinatory psychiatric illnesses
  • * History of psychosis
  • * Chronic narcotic usage defined as either having a pain contract with a pain management specialist and no narcotic usage for one month prior to hemorrhoidectomy.

Ages Eligible for Study

18 Years to 100 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Oklahoma,

Steven N Carter, MD, PRINCIPAL_INVESTIGATOR, University of Oklahoma

Study Record Dates

2025-07